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The Inhibition of TREK-1 K+ Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways.

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Title: The Inhibition of TREK-1 K+ Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways.
Authors: Miyano K; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Department of Dentistry, National Cancer Center Hospital, Tokyo 104-0045, Japan.; Laboratory of Pharmacotherapeutics, Faculty of Pharmacy, Juntendo University, Chiba 279-0013, Japan., Nonaka M; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan., Sakamoto M; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan., Murofushi M; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Yoshida Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan., Komura K; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Ohbuchi K; Tsumura Research Laboratories, Tsumura & Co., Inashiki 200-1192, Japan., Higami Y; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan., Fujii H; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan., Uezono Y; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Supportive and Palliative Care Research Support Office, National Cancer Center Hospital East, Chiba 277-8577, Japan.; Department of Comprehensive Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.
Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 30; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 30.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Inhibition of TREK-1 K<superscript>+</superscript> Channels via Multiple Compounds Contained in the Six Kamikihito Components, Potentially Stimulating Oxytocin Neuron Pathways.
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  Data: <searchLink fieldCode="AU" term="%22Miyano+K%22">Miyano K</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Department of Dentistry, National Cancer Center Hospital, Tokyo 104-0045, Japan.; Laboratory of Pharmacotherapeutics, Faculty of Pharmacy, Juntendo University, Chiba 279-0013, Japan.<br /><searchLink fieldCode="AU" term="%22Nonaka+M%22">Nonaka M</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.<br /><searchLink fieldCode="AU" term="%22Sakamoto+M%22">Sakamoto M</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.<br /><searchLink fieldCode="AU" term="%22Murofushi+M%22">Murofushi M</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshida+Y%22">Yoshida Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Komura+K%22">Komura K</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.<br /><searchLink fieldCode="AU" term="%22Ohbuchi+K%22">Ohbuchi K</searchLink>; Tsumura Research Laboratories, Tsumura & Co., Inashiki 200-1192, Japan.<br /><searchLink fieldCode="AU" term="%22Higami+Y%22">Higami Y</searchLink>; Laboratory of Molecular Pathology and Metabolic Disease, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba 278-8510, Japan.<br /><searchLink fieldCode="AU" term="%22Fujii+H%22">Fujii H</searchLink>; Laboratory of Medicinal Chemistry, School of Pharmacy, Kitasato University, Tokyo 108-8641, Japan.<br /><searchLink fieldCode="AU" term="%22Uezono+Y%22">Uezono Y</searchLink>; Department of Pain Control Research, The Jikei University School of Medicine, Tokyo 105-8461, Japan.; Supportive and Palliative Care Research Support Office, National Cancer Center Hospital East, Chiba 277-8577, Japan.; Department of Comprehensive Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8523, Japan.
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  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2024 Apr 30; Vol. 25 (9). <i>Date of Electronic Publication: </i>2024 Apr 30.
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