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Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway.

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Title: Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway.
Authors: Nóvoa E; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain., da Silva Lima N; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Gonzalez-Rellan MJ; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Chantada-Vazquez MDP; Proteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, A Coruña, Spain., Verheij J; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Rodriguez A; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain., Esquinas-Roman EM; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain., Fondevila MF; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Koning M; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands., Fernandez U; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain., Cabaleiro A; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Parracho T; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Iglesias-Moure J; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Seoane S; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Porteiro B; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Escudero A; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain., Senra A; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., Perez-Fernandez R; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain., López M; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain., Fidalgo M; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain., Guallar D; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain., Martinez-Chantar ML; Liver Disease Lab, BRTA CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Derio, Bizkaia, Spain., Dieguez C; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain., Varela-Rey M; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain., Prevot V; Univ. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, UMR-S 1172, European Genomic Institute for Diabetes (EGID), Lille, France., Schwaninger M; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany., Meijnikman A; Department of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands., Bravo SB; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain., Frühbeck G; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain., Nogueiras R; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain.; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain.
Source: Hepatology (Baltimore, Md.) [Hepatology] 2025 May 01; Vol. 81 (5), pp. 1535-1552. Date of Electronic Publication: 2024 May 16.
Publication Type: Journal Article
Journal Info: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Mitochondrial antiviral signaling protein enhances MASLD progression through the ERK/TNFα/NFκβ pathway.
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  Data: <searchLink fieldCode="AU" term="%22Nóvoa+E%22">Nóvoa E</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22da+Silva+Lima+N%22">da Silva Lima N</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Rellan+MJ%22">Gonzalez-Rellan MJ</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Chantada-Vazquez+MDP%22">Chantada-Vazquez MDP</searchLink>; Proteomic Unit, Health Research Institute of Santiago de Compostela (IDIS), Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Verheij+J%22">Verheij J</searchLink>; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rodriguez+A%22">Rodriguez A</searchLink>; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22Esquinas-Roman+EM%22">Esquinas-Roman EM</searchLink>; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Fondevila+MF%22">Fondevila MF</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Koning+M%22">Koning M</searchLink>; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Fernandez+U%22">Fernandez U</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Cabaleiro+A%22">Cabaleiro A</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Parracho+T%22">Parracho T</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Iglesias-Moure+J%22">Iglesias-Moure J</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Seoane+S%22">Seoane S</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Porteiro+B%22">Porteiro B</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Escudero+A%22">Escudero A</searchLink>; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Senra+A%22">Senra A</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22Perez-Fernandez+R%22">Perez-Fernandez R</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.<br /><searchLink fieldCode="AU" term="%22López+M%22">López M</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Fidalgo+M%22">Fidalgo M</searchLink>; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Guallar+D%22">Guallar D</searchLink>; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Martinez-Chantar+ML%22">Martinez-Chantar ML</searchLink>; Liver Disease Lab, BRTA CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Derio, Bizkaia, Spain.<br /><searchLink fieldCode="AU" term="%22Dieguez+C%22">Dieguez C</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22Varela-Rey+M%22">Varela-Rey M</searchLink>; Gene Regulatory Control in Disease Laboratory, Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Prevot+V%22">Prevot V</searchLink>; Univ. Lille, Inserm, CHU Lille, Laboratory of Development and Plasticity of the Neuroendocrine Brain, Lille Neuroscience & Cognition, UMR-S 1172, European Genomic Institute for Diabetes (EGID), Lille, France.<br /><searchLink fieldCode="AU" term="%22Schwaninger+M%22">Schwaninger M</searchLink>; Institute for Experimental and Clinical Pharmacology and Toxicology, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Meijnikman+A%22">Meijnikman A</searchLink>; Department of Internal and Experimental Vascular Medicine, Amsterdam University Medical Centers, Location AMC, Amsterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bravo+SB%22">Bravo SB</searchLink>; CIBER Fisiopatologia de la Obesidad y Nutrición (CIBERobn), A Coruña, Spain.<br /><searchLink fieldCode="AU" term="%22Frühbeck+G%22">Frühbeck G</searchLink>; Department of Pathology, Amsterdam University Medical Center, Amsterdam, The Netherlands.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain.<br /><searchLink fieldCode="AU" term="%22Nogueiras+R%22">Nogueiras R</searchLink>; Department of Physiology, CIMUS, University of Santiago de Compostela, Santiago de Compostela, Spain.; Department of Endocrinology & Nutrition, Metabolic Research Laboratory, Clínica Universidad de Navarra, University of Navarra, IdiSNA, Navarra, Spain.; Galician Agency of Innovation (GAIN), Xunta de Galicia, Santiago de Compostela, Spain.
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  Data: <searchLink fieldCode="JN" term="%228302946%22">Hepatology (Baltimore, Md.)</searchLink> [Hepatology] 2025 May 01; Vol. 81 (5), pp. 1535-1552. <i>Date of Electronic Publication: </i>2024 May 16.
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