Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.

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Title: Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
Authors: Wang S; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Chan KW; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Wei D; Laboratory of Immune Regulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Ma X; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Liu S; SYL Consulting, Thousand Oak, CA, 91320, USA., Hu G; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Park S; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA., Pan R; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Gu Y; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Nazzari AF; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Olia AS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Xu K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Lin BC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Louder MK; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., McKee K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Doria-Rose NA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Montefiori D; Department of Surgery, Duke University, Durham, NC, 27710, USA., Seaman MS; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA., Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Arthos J; Laboratory of Immune Regulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA., Kong XP; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA., Lu S; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA. shan.lu@umassmed.edu.
Source: Nature communications [Nat Commun] 2024 May 21; Vol. 15 (1), pp. 4301. Date of Electronic Publication: 2024 May 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Human CD4-binding site antibody elicited by polyvalent DNA prime-protein boost vaccine neutralizes cross-clade tier-2-HIV strains.
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  Data: <searchLink fieldCode="AU" term="%22Wang+S%22">Wang S</searchLink>; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.<br /><searchLink fieldCode="AU" term="%22Chan+KW%22">Chan KW</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA.<br /><searchLink fieldCode="AU" term="%22Wei+D%22">Wei D</searchLink>; Laboratory of Immune Regulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; SYL Consulting, Thousand Oak, CA, 91320, USA.<br /><searchLink fieldCode="AU" term="%22Hu+G%22">Hu G</searchLink>; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.<br /><searchLink fieldCode="AU" term="%22Park+S%22">Park S</searchLink>; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA.<br /><searchLink fieldCode="AU" term="%22Pan+R%22">Pan R</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA.<br /><searchLink fieldCode="AU" term="%22Gu+Y%22">Gu Y</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Nazzari+AF%22">Nazzari AF</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Olia+AS%22">Olia AS</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Xu+K%22">Xu K</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Lin+BC%22">Lin BC</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Louder+MK%22">Louder MK</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22McKee+K%22">McKee K</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Doria-Rose+NA%22">Doria-Rose NA</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Montefiori+D%22">Montefiori D</searchLink>; Department of Surgery, Duke University, Durham, NC, 27710, USA.<br /><searchLink fieldCode="AU" term="%22Seaman+MS%22">Seaman MS</searchLink>; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 02115, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+T%22">Zhou T</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Kwong+PD%22">Kwong PD</searchLink>; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Arthos+J%22">Arthos J</searchLink>; Laboratory of Immune Regulation, National Institute of Allergy and Infectious Diseases, NIH, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Kong+XP%22">Kong XP</searchLink>; Department of Biochemistry and Molecular Pharmacology, New York University Grossman School of Medicine, New York, NY, 10016, USA.<br /><searchLink fieldCode="AU" term="%22Lu+S%22">Lu S</searchLink>; Department of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, 01655, USA. shan.lu@umassmed.edu.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2024 May 21; Vol. 15 (1), pp. 4301. <i>Date of Electronic Publication: </i>2024 May 21.
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