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Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.

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Title: Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.
Authors: Wisialowski TA; Pfizer, Groton, CT, USA. Electronic address: todd.a.wisialowski@pfizer.com., Ether N; Amgen Inc., Thousand Oaks, CA, USA., Foley CM; AbbVie, North Chicago, IL, USA., Kleiman R; Clario, Philadelphia, PA, USA., Koshman Y; AbbVie, North Chicago, IL, USA., Leishman D; Eli Lilly and Company, Indianapolis, IN, USA., Martel E; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany., Nichols JV; Labcorp, Madison, WI, USA., Popp J; Labcorp, Madison, WI, USA., Rajamani S; Johnson & Johnson Innovative Medicine, CA, USA., Riley S; Pfizer, Groton, CT, USA., Rossman EI; GSK, Collegeville, PA, USA., Vargas HM; Amgen Inc., Thousand Oaks, CA, USA.
Source: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2024 Jul-Aug; Vol. 128, pp. 107515. Date of Electronic Publication: 2024 May 20.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.
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  Data: <searchLink fieldCode="AU" term="%22Wisialowski+TA%22">Wisialowski TA</searchLink>; Pfizer, Groton, CT, USA. Electronic address: todd.a.wisialowski@pfizer.com.<br /><searchLink fieldCode="AU" term="%22Ether+N%22">Ether N</searchLink>; Amgen Inc., Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Foley+CM%22">Foley CM</searchLink>; AbbVie, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Kleiman+R%22">Kleiman R</searchLink>; Clario, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Koshman+Y%22">Koshman Y</searchLink>; AbbVie, North Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Leishman+D%22">Leishman D</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Martel+E%22">Martel E</searchLink>; Boehringer Ingelheim Pharma GmbH & Co. KG, Biberach an der Riss, Germany.<br /><searchLink fieldCode="AU" term="%22Nichols+JV%22">Nichols JV</searchLink>; Labcorp, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Popp+J%22">Popp J</searchLink>; Labcorp, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Rajamani+S%22">Rajamani S</searchLink>; Johnson & Johnson Innovative Medicine, CA, USA.<br /><searchLink fieldCode="AU" term="%22Riley+S%22">Riley S</searchLink>; Pfizer, Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Rossman+EI%22">Rossman EI</searchLink>; GSK, Collegeville, PA, USA.<br /><searchLink fieldCode="AU" term="%22Vargas+HM%22">Vargas HM</searchLink>; Amgen Inc., Thousand Oaks, CA, USA.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9206091 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-488X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210568719%22">10568719 </searchLink><i>NLM ISO Abbreviation: </i>J Pharmacol Toxicol Methods <i>Subsets: </i>MEDLINE
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