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Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia.

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Title: Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia.
Authors: Montalban-Bravo G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Thongon N; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rodriguez-Sevilla JJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ma F; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA., Ganan-Gomez I; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Yang H; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kim YJ; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Adema V; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wildeman B; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tanaka T; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Darbaniyan F; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Al-Atrash G; Department of Stem Cell Transplantation and Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dwyer K; Department of Stem Cell Transplantation and Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Loghavi S; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kanagal-Shamanna R; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Song X; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang J; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Takahashi K; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kantarjian H; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Garcia-Manero G; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Colla S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: scolla@mdanderson.org.
Source: Cell reports. Medicine [Cell Rep Med] 2024 Jun 18; Vol. 5 (6), pp. 101585. Date of Electronic Publication: 2024 May 22.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE
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  Data: Targeting MCL1-driven anti-apoptotic pathways overcomes blast progression after hypomethylating agent failure in chronic myelomonocytic leukemia.
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  Data: <searchLink fieldCode="AU" term="%22Montalban-Bravo+G%22">Montalban-Bravo G</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Thongon+N%22">Thongon N</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Sevilla+JJ%22">Rodriguez-Sevilla JJ</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ma+F%22">Ma F</searchLink>; Department of Molecular, Cell and Developmental Biology, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ganan-Gomez+I%22">Ganan-Gomez I</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kim+YJ%22">Kim YJ</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Adema+V%22">Adema V</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wildeman+B%22">Wildeman B</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tanaka+T%22">Tanaka T</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Darbaniyan+F%22">Darbaniyan F</searchLink>; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Al-Atrash+G%22">Al-Atrash G</searchLink>; Department of Stem Cell Transplantation and Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Dwyer+K%22">Dwyer K</searchLink>; Department of Stem Cell Transplantation and Hematopoietic Biology and Malignancy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Loghavi+S%22">Loghavi S</searchLink>; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kanagal-Shamanna+R%22">Kanagal-Shamanna R</searchLink>; Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Song+X%22">Song X</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+J%22">Zhang J</searchLink>; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Takahashi+K%22">Takahashi K</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kantarjian+H%22">Kantarjian H</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Manero+G%22">Garcia-Manero G</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Colla+S%22">Colla S</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: scolla@mdanderson.org.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2024 Jun 18; Vol. 5 (6), pp. 101585. <i>Date of Electronic Publication: </i>2024 May 22.
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