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Volenrelaxin (LY3540378) increases renal plasma flow: a randomized Phase 1 trial.

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Title: Volenrelaxin (LY3540378) increases renal plasma flow: a randomized Phase 1 trial.
Authors: Tham LS; Global Pharmacokinetics, Pharmacodynamics and Pharmacometrics, Lilly Centre for Clinical Pharmacology Pte Ltd, Singapore, Singapore., Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Hanzeplein, Groningen, Netherlands., Wang X; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA., Verdino P; Computational Science and Protein Engineering, Lilly Biotechnology Center, San Diego, CA, USA., Saifan CG; Global Patient Safety and Pharmacovigilance-Oncology, Abbvie, IL, USA., Benson EA; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA., Goldsmith P; Exploratory Medicine and Pharmacology, Eli Lilly and Company, Bracknell, UK., Wang Z; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA., Testani JM; Department of Medicine, Division of Cardiovascular Medicine, Yale University, CT, USA., Haupt A; Diabetes and Metabolic Research, Eli Lilly and Company, Indianapolis, IN, USA., Sam F; Diabetes and Metabolic Research, Eli Lilly and Company, Indianapolis, IN, USA., Cherney DZI; Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2024 Dec 20; Vol. 40 (1), pp. 109-122.
Publication Type: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Volenrelaxin (LY3540378) increases renal plasma flow: a randomized Phase 1 trial.
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  Data: <searchLink fieldCode="AU" term="%22Tham+LS%22">Tham LS</searchLink>; Global Pharmacokinetics, Pharmacodynamics and Pharmacometrics, Lilly Centre for Clinical Pharmacology Pte Ltd, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Heerspink+HJL%22">Heerspink HJL</searchLink>; Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Hanzeplein, Groningen, Netherlands.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Verdino+P%22">Verdino P</searchLink>; Computational Science and Protein Engineering, Lilly Biotechnology Center, San Diego, CA, USA.<br /><searchLink fieldCode="AU" term="%22Saifan+CG%22">Saifan CG</searchLink>; Global Patient Safety and Pharmacovigilance-Oncology, Abbvie, IL, USA.<br /><searchLink fieldCode="AU" term="%22Benson+EA%22">Benson EA</searchLink>; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Goldsmith+P%22">Goldsmith P</searchLink>; Exploratory Medicine and Pharmacology, Eli Lilly and Company, Bracknell, UK.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Complications and Outcomes Research, Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Testani+JM%22">Testani JM</searchLink>; Department of Medicine, Division of Cardiovascular Medicine, Yale University, CT, USA.<br /><searchLink fieldCode="AU" term="%22Haupt+A%22">Haupt A</searchLink>; Diabetes and Metabolic Research, Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Sam+F%22">Sam F</searchLink>; Diabetes and Metabolic Research, Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Cherney+DZI%22">Cherney DZI</searchLink>; Department of Medicine, Division of Nephrology, University Health Network, Toronto, Ontario, Canada.; Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
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  Data: <searchLink fieldCode="JN" term="%228706402%22">Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association</searchLink> [Nephrol Dial Transplant] 2024 Dec 20; Vol. 40 (1), pp. 109-122.
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  Data: Journal Article; Randomized Controlled Trial; Clinical Trial, Phase I
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Oxford+University+Press%22">Oxford University Press </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8706402 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1460-2385 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209310509%22">09310509 </searchLink><i>NLM ISO Abbreviation: </i>Nephrol Dial Transplant <i>Subsets: </i>MEDLINE
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        Value: 10.1093/ndt/gfae112
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              Text: 2024 Dec 20
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