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A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells.

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Title: A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells.
Authors: Polini B; Department of Pathology, University of Pisa, 56100 Pisa, Italy., Zallocco L; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy., Gado F; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy., Ferrisi R; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy., Ricardi C; Department of Pathology, University of Pisa, 56100 Pisa, Italy., Zuccarini M; Department of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio of Chieti-Pescara, 66100 Chieti, Italy., Carnicelli V; Department of Pathology, University of Pisa, 56100 Pisa, Italy., Manera C; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy., Ronci M; Department of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.; Interuniversitary Consortium for Engineering and Medicine (COIIM), 86100 Campobasso, Italy., Lucacchini A; Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy., Zucchi R; Department of Pathology, University of Pisa, 56100 Pisa, Italy., Giusti L; School of Pharmacy, University of Camerino, 62032 Camerino, Italy., Chiellini G; Department of Pathology, University of Pisa, 56100 Pisa, Italy.
Source: Cells [Cells] 2024 May 19; Vol. 13 (10). Date of Electronic Publication: 2024 May 19.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: A Proteomic Approach Identified TFEB as a Key Player in the Protective Action of Novel CB2R Bitopic Ligand FD22a against the Deleterious Effects Induced by β-Amyloid in Glial Cells.
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  Data: <searchLink fieldCode="AU" term="%22Polini+B%22">Polini B</searchLink>; Department of Pathology, University of Pisa, 56100 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Zallocco+L%22">Zallocco L</searchLink>; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Gado+F%22">Gado F</searchLink>; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Ferrisi+R%22">Ferrisi R</searchLink>; Department of Pharmaceutical Sciences, University of Milan, 20133 Milano, Italy.; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Ricardi+C%22">Ricardi C</searchLink>; Department of Pathology, University of Pisa, 56100 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Zuccarini+M%22">Zuccarini M</searchLink>; Department of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.<br /><searchLink fieldCode="AU" term="%22Carnicelli+V%22">Carnicelli V</searchLink>; Department of Pathology, University of Pisa, 56100 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Manera+C%22">Manera C</searchLink>; Department of Pharmacy, University of Pisa, 56126 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Ronci+M%22">Ronci M</searchLink>; Department of Medical, Oral and Biotechnological Sciences, University G. D'Annunzio of Chieti-Pescara, 66100 Chieti, Italy.; Interuniversitary Consortium for Engineering and Medicine (COIIM), 86100 Campobasso, Italy.<br /><searchLink fieldCode="AU" term="%22Lucacchini+A%22">Lucacchini A</searchLink>; Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Zucchi+R%22">Zucchi R</searchLink>; Department of Pathology, University of Pisa, 56100 Pisa, Italy.<br /><searchLink fieldCode="AU" term="%22Giusti+L%22">Giusti L</searchLink>; School of Pharmacy, University of Camerino, 62032 Camerino, Italy.<br /><searchLink fieldCode="AU" term="%22Chiellini+G%22">Chiellini G</searchLink>; Department of Pathology, University of Pisa, 56100 Pisa, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101600052%22">Cells</searchLink> [Cells] 2024 May 19; Vol. 13 (10). <i>Date of Electronic Publication: </i>2024 May 19.
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