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Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.

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Title: Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
Authors: Prchalova E; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Andrys R; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Pejchal J; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic., Kohoutova Z; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Knittelova K; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Hofmanova T; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Skarka A; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic., Dlabkova A; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic., Psotka M; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic., Prchal L; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic., Musilek K; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic., Karasova JZ; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic. zdarovakarasovaj@unob.cz.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. zdarovakarasovaj@unob.cz., Malinak D; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic. david.malinak@uhk.cz.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. david.malinak@uhk.cz.
Source: Archives of toxicology [Arch Toxicol] 2024 Sep; Vol. 98 (9), pp. 2937-2952. Date of Electronic Publication: 2024 May 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Brominated oxime nucleophiles are efficiently reactivating cholinesterases inhibited by nerve agents.
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  Data: <searchLink fieldCode="AU" term="%22Prchalova+E%22">Prchalova E</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Andrys+R%22">Andrys R</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Pejchal+J%22">Pejchal J</searchLink>; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kohoutova+Z%22">Kohoutova Z</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Knittelova+K%22">Knittelova K</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Hofmanova+T%22">Hofmanova T</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Skarka+A%22">Skarka A</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Dlabkova+A%22">Dlabkova A</searchLink>; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Psotka+M%22">Psotka M</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Prchal+L%22">Prchal L</searchLink>; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Musilek+K%22">Musilek K</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Karasova+JZ%22">Karasova JZ</searchLink>; University of Defence, Military Faculty of Medicine, Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 01, Hradec Kralove, Czech Republic. zdarovakarasovaj@unob.cz.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. zdarovakarasovaj@unob.cz.<br /><searchLink fieldCode="AU" term="%22Malinak+D%22">Malinak D</searchLink>; University of Hradec Kralove, Faculty of Science, Department of Chemistry, Rokitanskeho 62, 500 03, Hradec Kralove, Czech Republic. david.malinak@uhk.cz.; University Hospital in Hradec Kralove, Biomedical Research Center, Sokolska 581, 500 05, Hradec Kralove, Czech Republic. david.malinak@uhk.cz.
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  Data: <searchLink fieldCode="JN" term="%220417615%22">Archives of toxicology</searchLink> [Arch Toxicol] 2024 Sep; Vol. 98 (9), pp. 2937-2952. <i>Date of Electronic Publication: </i>2024 May 24.
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        Value: 10.1007/s00204-024-03791-6
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