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A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma.

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Title: A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma.
Authors: Pilcher WC; Coultier Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA., Yao L; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Gonzalez-Kozlova E; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pita-Juarez Y; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Karagkouni D; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Acharya CR; MMRF, Norwalk, CT, USA., Michaud ME; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA., Hamilton M; MMRF, Norwalk, CT, USA., Nanda S; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Song Y; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Sato K; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Wang JT; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Satpathy S; Department of Biomedical Informatics, Emory School of Medicine, Atlanta, GA, USA., Ma Y; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Schulman J; MMRF, Norwalk, CT, USA., D'Souza D; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Jayasinghe RG; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Cheloni G; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Bakhtiari M; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA., Pabustan N; MMRF, Norwalk, CT, USA., Nie K; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Foltz JA; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Saldarriaga I; Beth Israel Deaconess Medical Center, Boston, MA, USA., Alaaeldin R; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA., Lepisto E; MMRF, Norwalk, CT, USA., Chen R; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fiala MA; Bone Marrow Transplantation & Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA., Thomas BE; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA., Cook A; MMRF, Norwalk, CT, USA., Dos Santos JV; Tisch Cancer Institute, Department of Immunology and Immunotherapy, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chiang IL; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Figueiredo I; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fortier J; Bone Marrow Transplantation & Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA., Slade M; Bone Marrow Transplantation & Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA., Oh ST; Division of Hematology, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA.; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.; Immunomonitoring Laboratory, Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO, USA., Rettig MP; Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA., Anderson E; Mayo Clinic, Rochester, MN, USA., Li Y; Mayo Clinic, Rochester, MN, USA., Dasari S; Mayo Clinic, Rochester, MN, USA., Strausbauch MA; Mayo Clinic, Rochester, MN, USA., Simon VA; Mayo Clinic, Rochester, MN, USA., Rahman AH; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen Z; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lagana A; Tisch Cancer Institute, Department of Immunology and Immunotherapy, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., DiPersio JF; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA., Rosenblatt J; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cancer Center & Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA., Kim-Schulze S; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dhodapkar MV; Department of Hematology Oncology, Emory School of Medicine, Atlanta, GA, USA.; Winship Cancer Institute, Emory School of Medicine, Atlanta, GA, USA., Lonial S; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta., Kumar S; Mayo Clinic, Rochester, MN, USA., Bhasin SS; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA., Kourelis T; Mayo Clinic, Rochester, MN, USA., Vij R; Bone Marrow Transplantation & Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA., Avigan D; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Cancer Center & Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA, USA., Cho HJ; MMRF, Norwalk, CT, USA., Mulligan G; MMRF, Norwalk, CT, USA., Ding L; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.; Siteman Cancer Center, Washington University in St. Louis, St. Louis, MO, USA., Gnjatic S; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Vlachos IS; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Spatial Technologies Unit, Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA.; Cancer Center & Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA., Bhasin M; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory School of Medicine, Atlanta, GA, USA.; Coultier Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
Corporate Authors: Immune Atlas Consortium
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 17. Date of Electronic Publication: 2024 May 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
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AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: A single-cell atlas characterizes dysregulation of the bone marrow immune microenvironment associated with outcomes in multiple myeloma.
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  Data: <searchLink fieldCode="AU" term="%22Pilcher+WC%22">Pilcher WC</searchLink>; Coultier Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Yao+L%22">Yao L</searchLink>; Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Kozlova+E%22">Gonzalez-Kozlova E</searchLink>; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Pita-Juarez+Y%22">Pita-Juarez Y</searchLink>; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Karagkouni+D%22">Karagkouni D</searchLink>; Beth Israel Deaconess Medical Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; 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MMRF, Norwalk, CT, USA.<br /><searchLink fieldCode="AU" term="%22Chen+R%22">Chen R</searchLink>; Human Immune Monitoring Center, Tisch Cancer Institute, Department of Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Fiala+MA%22">Fiala MA</searchLink>; Bone Marrow Transplantation & Leukemia Section, Division of Oncology, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Thomas+BE%22">Thomas BE</searchLink>; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Cook+A%22">Cook A</searchLink>; MMRF, Norwalk, CT, USA.<br /><searchLink fieldCode="AU" term="%22Dos+Santos+JV%22">Dos Santos JV</searchLink>; Tisch Cancer Institute, Department of Immunology and Immunotherapy, Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Chiang+IL%22">Chiang IL</searchLink>; 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Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Spatial Technologies Unit, Harvard Medical School Initiative for RNA Medicine, Boston, MA, USA.; Cancer Center & Cancer Research Institute, Beth Israel Deaconess Medical Center, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Bhasin+M%22">Bhasin M</searchLink>; Department of Pediatrics, Emory School of Medicine, Atlanta, GA, USA.; Department of Biomedical Informatics, Emory School of Medicine, Atlanta, GA, USA.; Coultier Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.; Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA, USA.
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        Value: 10.1101/2024.05.15.593193
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      – PersonEntity:
          Name:
            NameFull: Lagana A
      – PersonEntity:
          Name:
            NameFull: DiPersio JF
      – PersonEntity:
          Name:
            NameFull: Rosenblatt J
      – PersonEntity:
          Name:
            NameFull: Kim-Schulze S
      – PersonEntity:
          Name:
            NameFull: Dhodapkar MV
      – PersonEntity:
          Name:
            NameFull: Lonial S
      – PersonEntity:
          Name:
            NameFull: Kumar S
      – PersonEntity:
          Name:
            NameFull: Bhasin SS
      – PersonEntity:
          Name:
            NameFull: Kourelis T
      – PersonEntity:
          Name:
            NameFull: Vij R
      – PersonEntity:
          Name:
            NameFull: Avigan D
      – PersonEntity:
          Name:
            NameFull: Cho HJ
      – PersonEntity:
          Name:
            NameFull: Mulligan G
      – PersonEntity:
          Name:
            NameFull: Ding L
      – PersonEntity:
          Name:
            NameFull: Gnjatic S
      – PersonEntity:
          Name:
            NameFull: Vlachos IS
      – PersonEntity:
          Name:
            NameFull: Bhasin M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 17
              M: 05
              Text: 2024 May 17
              Type: published
              Y: 2024
          Identifiers:
            – Type: issn-electronic
              Value: 2692-8205
          Titles:
            – TitleFull: BioRxiv : the preprint server for biology
              Type: main
ResultId 1