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CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques.

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Title: CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques.
Authors: Simonson AW; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Zeppa JJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Bucsan AN; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Chao MC; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health; Boston, MA, USA., Pokkali S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Hopkins F; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health; Boston, MA, USA., Chase MR; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health; Boston, MA, USA., Vickers AJ; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health; Boston, MA, USA., Sutton MS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Winchell CG; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Myers AJ; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Ameel CL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Kelly R; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Krouse B; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Hood LE; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Li J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Lehman CC; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Kamath M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Tomko J; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Rodgers MA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Donlan R; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Chishti H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Jacob Borish H; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Klein E; Division of Animal Laboratory Resources, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Scanga CA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Fortune S; Ragon Institute of MGH, MIT, and Harvard; Cambridge, MA, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health; Boston, MA, USA.; Broad Institute of MIT and Harvard; Cambridge, MA, USA., Lin PL; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Department of Pediatrics, Children's Hospital of the University of Pittsburgh of UPMC; Pittsburgh, PA, USA., Maiello P; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA., Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Darrah PA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Seder RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH); Bethesda, MD, USA., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.; Center for Vaccine Research, University of Pittsburgh School of Medicine; Pittsburgh, PA, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2024 May 17. Date of Electronic Publication: 2024 May 17.
Publication Type: Preprint; Journal Article
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: CD4 T cells and CD8α+ lymphocytes are necessary for intravenous BCG-induced protection against tuberculosis in macaques.
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