ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages.

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Title: ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages.
Authors: Bates TA; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Trank-Greene M; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Wrynla XH; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Anastas A; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Gurmessa SK; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Merutka IR; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Dixon SD; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Shumate A; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, United States., Groncki AR; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Parson MAH; Department of Biochemistry and Microbiology, University of Victoria, Victoria, Canada., Ingram JR; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, United States., Barklis E; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States., Burke JE; Department of Biochemistry and Microbiology, University of Victoria, Victoria, Canada.; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, Canada., Shinde U; Department of Chemical Physiology and Biochemistry, Oregon Health & Science University, Portland, United States., Ploegh HL; Program in Cellular and Molecular Medicine, Boston Children's Hospital, Harvard Medical School, Boston, United States., Tafesse FG; Department of Molecular Microbiology and Immunology, Oregon Health & Sciences University, Portland, United States.
Source: ELife [Elife] 2024 May 28; Vol. 12. Date of Electronic Publication: 2024 May 28.
Publication Type: Journal Article
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
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  Data: ESAT-6 undergoes self-association at phagosomal pH and an ESAT-6-specific nanobody restricts M. tuberculosis growth in macrophages.
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