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JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.

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Title: JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
Authors: Redmer T; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. torben.redmer@vetmeduni.ac.at., Raigel M; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria., Sternberg C; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Biochemical Institute, University of Kiel, Kiel, 24098, Germany., Ziegler R; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Cell Biology, Charles University, Prague, Czech Republic and Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University (BIOCEV), Vestec u Prahy, Czech Republic., Probst C; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria., Lindner D; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria., Aufinger A; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria., Limberger T; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Center for Biomarker Research in Medicine (CBmed) Vienna, Core-Lab2, Medical University of Vienna, Vienna, 1090, Austria., Trachtova K; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic., Kodajova P; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Högler S; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Schlederer M; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria., Stoiber S; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, 1090, Austria., Oberhuber M; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria., Bolis M; Institute of Oncology Research, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, 6500, TI, Switzerland.; Computational Oncology Unit, Department of Oncology, Istituto di Richerche Farmacologiche 'Mario Negri' IRCCS, Milano, 20156, Italy.; Bioinformatics Core Unit, Swiss Institute of Bioinformatics, Bellinzona, 6500, TI, Switzerland., Neubauer HA; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Miranda S; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Tomberger M; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria., Harbusch NS; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria., Garces de Los Fayos Alonso I; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria., Sternberg F; Institute of Physiology, Pathophysiology and Biophysics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria., Moriggl R; Department of Biosciences and Medical Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Theurillat JP; Institute of Oncology Research, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, 6500, TI, Switzerland., Tichy B; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic., Bystry V; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic., Persson JL; Department of Molecular Biology, Umeå University, Umeå, 901 87, Sweden.; Department of Biomedical Sciences, Malmö Universitet, Malmö, 206 06, Sweden., Mathas S; Charité-Universitätsmedizin Berlin, Hematology, Oncology and Tumor Immunology, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, 10117, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Group Biology of Malignant Lymphomas, Berlin, 13125, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the MDC and the Charité, Berlin, Germany., Aberger F; Department of Biosciences and Medical Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria., Strobl B; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Pospisilova S; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic., Merkel O; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria., Egger G; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria., Lagger S; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. sabine.lagger@vetmeduni.ac.at., Kenner L; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. lukas.kenner@meduniwien.ac.at.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria. lukas.kenner@meduniwien.ac.at.; Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.
Source: Molecular cancer [Mol Cancer] 2024 May 29; Vol. 23 (1), pp. 114. Date of Electronic Publication: 2024 May 29.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: JUN mediates the senescence associated secretory phenotype and immune cell recruitment to prevent prostate cancer progression.
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  Data: <searchLink fieldCode="AU" term="%22Redmer+T%22">Redmer T</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. torben.redmer@vetmeduni.ac.at.<br /><searchLink fieldCode="AU" term="%22Raigel+M%22">Raigel M</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Sternberg+C%22">Sternberg C</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Biochemical Institute, University of Kiel, Kiel, 24098, Germany.<br /><searchLink fieldCode="AU" term="%22Ziegler+R%22">Ziegler R</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Cell Biology, Charles University, Prague, Czech Republic and Biotechnology and Biomedicine Centre of the Academy of Sciences and Charles University (BIOCEV), Vestec u Prahy, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Probst+C%22">Probst C</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Lindner+D%22">Lindner D</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Aufinger+A%22">Aufinger A</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Limberger+T%22">Limberger T</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Center for Biomarker Research in Medicine (CBmed) Vienna, Core-Lab2, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Trachtova+K%22">Trachtova K</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Kodajova+P%22">Kodajova P</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.<br /><searchLink fieldCode="AU" term="%22Högler+S%22">Högler S</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.<br /><searchLink fieldCode="AU" term="%22Schlederer+M%22">Schlederer M</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Stoiber+S%22">Stoiber S</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.; Department of Biomedical Imaging and Image-Guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, 1090, Austria.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Oberhuber+M%22">Oberhuber M</searchLink>; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria.<br /><searchLink fieldCode="AU" term="%22Bolis+M%22">Bolis M</searchLink>; Institute of Oncology Research, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, 6500, TI, Switzerland.; Computational Oncology Unit, Department of Oncology, Istituto di Richerche Farmacologiche 'Mario Negri' IRCCS, Milano, 20156, Italy.; Bioinformatics Core Unit, Swiss Institute of Bioinformatics, Bellinzona, 6500, TI, Switzerland.<br /><searchLink fieldCode="AU" term="%22Neubauer+HA%22">Neubauer HA</searchLink>; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Institute of Medical Biochemistry, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.<br /><searchLink fieldCode="AU" term="%22Miranda+S%22">Miranda S</searchLink>; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.<br /><searchLink fieldCode="AU" term="%22Tomberger+M%22">Tomberger M</searchLink>; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria.<br /><searchLink fieldCode="AU" term="%22Harbusch+NS%22">Harbusch NS</searchLink>; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria.<br /><searchLink fieldCode="AU" term="%22Garces+de+Los+Fayos+Alonso+I%22">Garces de Los Fayos Alonso I</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Sternberg+F%22">Sternberg F</searchLink>; Institute of Physiology, Pathophysiology and Biophysics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.; Department of Nutritional Sciences, Faculty of Life Sciences, University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Moriggl+R%22">Moriggl R</searchLink>; Department of Biosciences and Medical Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria.<br /><searchLink fieldCode="AU" term="%22Theurillat+JP%22">Theurillat JP</searchLink>; Institute of Oncology Research, Bellinzona and Faculty of Biomedical Sciences, USI, Lugano, 6500, TI, Switzerland.<br /><searchLink fieldCode="AU" term="%22Tichy+B%22">Tichy B</searchLink>; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Bystry+V%22">Bystry V</searchLink>; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Persson+JL%22">Persson JL</searchLink>; Department of Molecular Biology, Umeå University, Umeå, 901 87, Sweden.; Department of Biomedical Sciences, Malmö Universitet, Malmö, 206 06, Sweden.<br /><searchLink fieldCode="AU" term="%22Mathas+S%22">Mathas S</searchLink>; Charité-Universitätsmedizin Berlin, Hematology, Oncology and Tumor Immunology, corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, 10117, Germany.; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Group Biology of Malignant Lymphomas, Berlin, 13125, Germany.; Experimental and Clinical Research Center (ECRC), a cooperation between the MDC and the Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Aberger+F%22">Aberger F</searchLink>; Department of Biosciences and Medical Biology, Cancer Cluster Salzburg, Paris-Lodron University of Salzburg, Salzburg, 5020, Austria.<br /><searchLink fieldCode="AU" term="%22Strobl+B%22">Strobl B</searchLink>; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria.<br /><searchLink fieldCode="AU" term="%22Pospisilova+S%22">Pospisilova S</searchLink>; CEITEC-Central European Institute of Technology, Masaryk University, Brno, 625 00, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Merkel+O%22">Merkel O</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Egger+G%22">Egger G</searchLink>; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria.<br /><searchLink fieldCode="AU" term="%22Lagger+S%22">Lagger S</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. sabine.lagger@vetmeduni.ac.at.<br /><searchLink fieldCode="AU" term="%22Kenner+L%22">Kenner L</searchLink>; Unit of Laboratory Animal Pathology, University of Veterinary Medicine Vienna, Vienna, 1210, Austria. lukas.kenner@meduniwien.ac.at.; Department of Pathology, Medical University of Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.; Christian Doppler Laboratory for Applied Metabolomics, Medical University of Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.; Center for Biomarker Research in Medicine, CBmed GmbH, Graz, 8010, Austria. lukas.kenner@meduniwien.ac.at.; Comprehensive Cancer Center, Medical University Vienna, Vienna, 1090, Austria. lukas.kenner@meduniwien.ac.at.
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