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Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators.

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Title: Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators.
Authors: Wang H; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., van de Bovenkamp FS; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Dijkstra DJ; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Abendstein L; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., Borggreven NV; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Pool J; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Zuijderduijn R; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands., Gstöttner C; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., Gelderman KA; Sanquin Diagnostic Services, Amsterdam, Netherlands., Damelang T; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands., Vidarsson G; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands., Blom AM; Department of Translational Medicine, Section of Medical Protein Chemistry, Lund University, Malmö, Sweden., Domínguez-Vega E; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands., Parren PWHI; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Gyes BV, Utrecht, Netherlands., Sharp TH; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands., Trouw LA; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
Source: Frontiers in immunology [Front Immunol] 2024 May 16; Vol. 15, pp. 1288597. Date of Electronic Publication: 2024 May 16 (Print Publication: 2024).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeted complement inhibition using bispecific antibodies that bind local antigens and endogenous complement regulators.
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  Data: <searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22van+de+Bovenkamp+FS%22">van de Bovenkamp FS</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Dijkstra+DJ%22">Dijkstra DJ</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Abendstein+L%22">Abendstein L</searchLink>; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Borggreven+NV%22">Borggreven NV</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Pool+J%22">Pool J</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Zuijderduijn+R%22">Zuijderduijn R</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Gstöttner+C%22">Gstöttner C</searchLink>; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Gelderman+KA%22">Gelderman KA</searchLink>; Sanquin Diagnostic Services, Amsterdam, Netherlands.<br /><searchLink fieldCode="AU" term="%22Damelang+T%22">Damelang T</searchLink>; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Vidarsson+G%22">Vidarsson G</searchLink>; Sanquin Research, Department of Experimental Immunohematology, Amsterdam, Netherlands.; Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences and Bijvoet Center for Biomolecular Research, Utrecht University, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Blom+AM%22">Blom AM</searchLink>; Department of Translational Medicine, Section of Medical Protein Chemistry, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Domínguez-Vega+E%22">Domínguez-Vega E</searchLink>; Center for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Parren+PWHI%22">Parren PWHI</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.; Gyes BV, Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Sharp+TH%22">Sharp TH</searchLink>; Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, Netherlands.<br /><searchLink fieldCode="AU" term="%22Trouw+LA%22">Trouw LA</searchLink>; Department of Immunology, Leiden University Medical Center, Leiden, Netherlands.
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