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Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.

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Title: Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.
Authors: Prasad K; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India., Devaraju N; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India., George A; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India., Ravi NS; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India., Paul J; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India., Mahalingam G; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India., Rajendiran V; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India., Panigrahi L; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India., Venkatesan V; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India., Lakhotiya K; Molecular Cardiology Research Institute, Tufts Medical Center, 800 Washington Street, Boston MA 02111, USA., Periyasami Y; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India., Pai AA; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India., Nakamura Y; Cell Engineering Division, RIKEN BioResource Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 3050074, Japan., Kurita R; Research and Development Department, Central Blood Institute Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan., Balasubramanian P; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India., Thangavel S; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India., Velayudhan SR; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India., Newby GA; Departments of Genetic Medicine and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Marepally S; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India., Srivastava A; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India., Mohankumar KM; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2024 May 03; Vol. 35 (2), pp. 102205. Date of Electronic Publication: 2024 May 03 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
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  Data: Precise correction of a spectrum of β-thalassemia mutations in coding and non-coding regions by base editors.
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  Data: <searchLink fieldCode="AU" term="%22Prasad+K%22">Prasad K</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22Devaraju+N%22">Devaraju N</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22George+A%22">George A</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.<br /><searchLink fieldCode="AU" term="%22Ravi+NS%22">Ravi NS</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.<br /><searchLink fieldCode="AU" term="%22Paul+J%22">Paul J</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22Mahalingam+G%22">Mahalingam G</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.<br /><searchLink fieldCode="AU" term="%22Rajendiran+V%22">Rajendiran V</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.<br /><searchLink fieldCode="AU" term="%22Panigrahi+L%22">Panigrahi L</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22Venkatesan+V%22">Venkatesan V</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.<br /><searchLink fieldCode="AU" term="%22Lakhotiya+K%22">Lakhotiya K</searchLink>; Molecular Cardiology Research Institute, Tufts Medical Center, 800 Washington Street, Boston MA 02111, USA.<br /><searchLink fieldCode="AU" term="%22Periyasami+Y%22">Periyasami Y</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.<br /><searchLink fieldCode="AU" term="%22Pai+AA%22">Pai AA</searchLink>; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India.<br /><searchLink fieldCode="AU" term="%22Nakamura+Y%22">Nakamura Y</searchLink>; Cell Engineering Division, RIKEN BioResource Center, 3-1-1 Koyadai, Tsukuba, Ibaraki 3050074, Japan.<br /><searchLink fieldCode="AU" term="%22Kurita+R%22">Kurita R</searchLink>; Research and Development Department, Central Blood Institute Blood Service Headquarters, Japanese Red Cross Society, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Balasubramanian+P%22">Balasubramanian P</searchLink>; Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala 695 011, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India.<br /><searchLink fieldCode="AU" term="%22Thangavel+S%22">Thangavel S</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.<br /><searchLink fieldCode="AU" term="%22Velayudhan+SR%22">Velayudhan SR</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India.<br /><searchLink fieldCode="AU" term="%22Newby+GA%22">Newby GA</searchLink>; Departments of Genetic Medicine and Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.<br /><searchLink fieldCode="AU" term="%22Marepally+S%22">Marepally S</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.<br /><searchLink fieldCode="AU" term="%22Srivastava+A%22">Srivastava A</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Department of Haematology, Christian Medical College & Hospital, Vellore 632 004, India.<br /><searchLink fieldCode="AU" term="%22Mohankumar+KM%22">Mohankumar KM</searchLink>; Centre for Stem Cell Research (a Unit of inStem, Bengaluru), Christian Medical College Campus, Bagayam, Vellore, Tamil Nadu 632002, India.; Manipal Academy of Higher Education, Karnataka 576104, India.
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