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In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection.

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Title: In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection.
Authors: Tkaczyk C; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA. Electronic address: christine.tkaczyk@astrazeneca.com., Newton M; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Gaithersburg, MD 20878, USA., Patnaik MM; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA., Thom G; AstraZeneca, Discovery Sciences, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK., Strain M; AstraZeneca, Biologics Engineering, BioPharmaceuticals R&D, Cambridge CB216GH, UK., Gamson A; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA., Daramola O; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK., Murthy A; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK., Douthwaite J; AstraZeneca, Discovery Sciences, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK., Stepanov O; Clinical Pharmacology and Pharmacometrics, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB2 8PA, UK., Boger E; Drug Metabolism and Pharmacokinetics, Research and Early Development, Respirator & immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Yang H; Clinical Pharmacology and Pharmacometrics, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, USA., Esser MT; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA., Lidwell A; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA., DiGiandomenico A; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA., Santos L; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Gaithersburg, MD 20878, USA., Sellman BR; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.
Source: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Aug 07; Vol. 32 (8), pp. 2505-2518. Date of Electronic Publication: 2024 May 31.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: In vivo mRNA expression of a multi-mechanistic mAb combination protects against Staphylococcus aureus infection.
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  Data: <searchLink fieldCode="AU" term="%22Tkaczyk+C%22">Tkaczyk C</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA. Electronic address: christine.tkaczyk@astrazeneca.com.<br /><searchLink fieldCode="AU" term="%22Newton+M%22">Newton M</searchLink>; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Patnaik+MM%22">Patnaik MM</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Thom+G%22">Thom G</searchLink>; AstraZeneca, Discovery Sciences, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK.<br /><searchLink fieldCode="AU" term="%22Strain+M%22">Strain M</searchLink>; AstraZeneca, Biologics Engineering, BioPharmaceuticals R&D, Cambridge CB216GH, UK.<br /><searchLink fieldCode="AU" term="%22Gamson+A%22">Gamson A</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Daramola+O%22">Daramola O</searchLink>; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK.<br /><searchLink fieldCode="AU" term="%22Murthy+A%22">Murthy A</searchLink>; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK.<br /><searchLink fieldCode="AU" term="%22Douthwaite+J%22">Douthwaite J</searchLink>; AstraZeneca, Discovery Sciences, BioPharmaceuticals R&D, Cambridge CB21 6GH, UK.<br /><searchLink fieldCode="AU" term="%22Stepanov+O%22">Stepanov O</searchLink>; Clinical Pharmacology and Pharmacometrics, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB2 8PA, UK.<br /><searchLink fieldCode="AU" term="%22Boger+E%22">Boger E</searchLink>; Drug Metabolism and Pharmacokinetics, Research and Early Development, Respirator & immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Yang+H%22">Yang H</searchLink>; Clinical Pharmacology and Pharmacometrics, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Esser+MT%22">Esser MT</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Lidwell+A%22">Lidwell A</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22DiGiandomenico+A%22">DiGiandomenico A</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Santos+L%22">Santos L</searchLink>; AstraZeneca, BioPharmaceutical Development, BioPharmaceuticals R&D, Gaithersburg, MD 20878, USA.<br /><searchLink fieldCode="AU" term="%22Sellman+BR%22">Sellman BR</searchLink>; AstraZeneca, Early Vaccines & Immune Therapies, Gaithersburg, MD 20878, USA.
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  Data: <searchLink fieldCode="JN" term="%22100890581%22">Molecular therapy : the journal of the American Society of Gene Therapy</searchLink> [Mol Ther] 2024 Aug 07; Vol. 32 (8), pp. 2505-2518. <i>Date of Electronic Publication: </i>2024 May 31.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>100890581 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1525-0024 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215250016%22">15250016 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther <i>Subsets: </i>MEDLINE
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