A PARP2-specific active site α-helix melts to permit DNA damage-induced enzymatic activation.
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| Title: | A PARP2-specific active site α-helix melts to permit DNA damage-induced enzymatic activation. |
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| Authors: | Smith-Pillet ES; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute.; Graduate Program in Biochemistry, Biophysics, Chemical Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19140-6059 USA., Billur R; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute., Langelier MF; Département de Biochimie et Médecine Moléculaire, Université de Montréal Montréal, (Québec), H3C 3J7 Canada., Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, NY 11439 USA., Pascal JM; Département de Biochimie et Médecine Moléculaire, Université de Montréal Montréal, (Québec), H3C 3J7 Canada., Black BE; Department of Biochemistry and Biophysics, Penn Center for Genome Integrity, Epigenetics Institute.; Graduate Program in Biochemistry, Biophysics, Chemical Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19140-6059 USA. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2024 May 20. Date of Electronic Publication: 2024 May 20. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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