Engineered Exosomes Containing microRNA-29b-2 and Targeting the Somatostatin Receptor Reduce Presenilin 1 Expression and Decrease the β-Amyloid Accumulation in the Brains of Mice with Alzheimer's Disease.
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| Title: | Engineered Exosomes Containing microRNA-29b-2 and Targeting the Somatostatin Receptor Reduce Presenilin 1 Expression and Decrease the β-Amyloid Accumulation in the Brains of Mice with Alzheimer's Disease. |
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| Authors: | Lin EY; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan.; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan., Hsu SX; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan., Wu BH; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan., Deng YC; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan.; Everfront Biotech Inc, Taipei, Taiwan., Wuli W; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan., Li YS; Everfront Biotech Inc, Taipei, Taiwan., Lee JH; Everfront Biotech Inc, Taipei, Taiwan., Lin SZ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Hualien, Taiwan., Harn HJ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.; Department of Pathology, Hualien Tzu Chi Hospital, Hualien, Taiwan., Chiou TW; Department of Life Science and Graduate Institute of Biotechnology, National Dong Hwa University, Hualien, Taiwan. |
| Source: | International journal of nanomedicine [Int J Nanomedicine] 2024 May 29; Vol. 19, pp. 4977-4994. Date of Electronic Publication: 2024 May 29 (Print Publication: 2024). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1178-2013 |
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| DOI: | 10.2147/IJN.S442876 |
