Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?

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Title: Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?
Authors: Ambery P; Clinical Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Greasley PJ; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Menzies RI; Bioscience Renal, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Brynne L; Information Practice Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Kulkarni S; Department of Clinical Pharmacology and Therapeutics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB20QQ, U.K.; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K., Oscarsson J; Clinical Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Davenport AP; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.
Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2024 Jun 05; Vol. 138 (11), pp. 687-697.
Publication Type: Journal Article; Review; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together?
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  Data: <searchLink fieldCode="AU" term="%22Ambery+P%22">Ambery P</searchLink>; Clinical Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Greasley+PJ%22">Greasley PJ</searchLink>; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Menzies+RI%22">Menzies RI</searchLink>; Bioscience Renal, Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Brynne+L%22">Brynne L</searchLink>; Information Practice Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Kulkarni+S%22">Kulkarni S</searchLink>; Department of Clinical Pharmacology and Therapeutics, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB20QQ, U.K.; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.<br /><searchLink fieldCode="AU" term="%22Oscarsson+J%22">Oscarsson J</searchLink>; Clinical Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Davenport+AP%22">Davenport AP</searchLink>; Division of Experimental Medicine and Immunotherapeutics, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Portland+Press+on+behalf+of+the+Medical+Research+Society+and+the+Biochemical+Society%22">Portland Press on behalf of the Medical Research Society and the Biochemical Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7905731 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1470-8736 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201435221%22">01435221 </searchLink><i>NLM ISO Abbreviation: </i>Clin Sci (Lond) <i>Subsets: </i>MEDLINE
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              Text: 2024 Jun 05
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