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iPSC-derived hindbrain organoids to evaluate escitalopram oxalate treatment responses targeting neuropsychiatric symptoms in Alzheimer's disease.

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Title: iPSC-derived hindbrain organoids to evaluate escitalopram oxalate treatment responses targeting neuropsychiatric symptoms in Alzheimer's disease.
Authors: Zivko C; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA., Sagar R; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA., Xydia A; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA., Lopez-Montes A; Department of Biomedical Engineering, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA., Mintzer J; Department of Health Sciences, Medical University of South Carolina, 29425, Charleston, SC, USA.; Ralph H. Johnson VA Healthcare System, 29401, Charleston, SC, USA., Rosenberg PB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA., Shade DM; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 21205, Baltimore, MD, USA., Porsteinsson AP; Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 14642, Rochester, NY, USA., Lyketsos CG; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.; Johns Hopkins Alzheimer's Disease Research Center, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA., Mahairaki V; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA. vmachai1@jhmi.edu.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA. vmachai1@jhmi.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2024 Nov; Vol. 29 (11), pp. 3644-3652. Date of Electronic Publication: 2024 Jun 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
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  Data: iPSC-derived hindbrain organoids to evaluate escitalopram oxalate treatment responses targeting neuropsychiatric symptoms in Alzheimer's disease.
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  Data: <searchLink fieldCode="AU" term="%22Zivko+C%22">Zivko C</searchLink>; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sagar+R%22">Sagar R</searchLink>; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Xydia+A%22">Xydia A</searchLink>; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Lopez-Montes+A%22">Lopez-Montes A</searchLink>; Department of Biomedical Engineering, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mintzer+J%22">Mintzer J</searchLink>; Department of Health Sciences, Medical University of South Carolina, 29425, Charleston, SC, USA.; Ralph H. Johnson VA Healthcare System, 29401, Charleston, SC, USA.<br /><searchLink fieldCode="AU" term="%22Rosenberg+PB%22">Rosenberg PB</searchLink>; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Shade+DM%22">Shade DM</searchLink>; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 21205, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Porsteinsson+AP%22">Porsteinsson AP</searchLink>; Department of Psychiatry, University of Rochester School of Medicine and Dentistry, 14642, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lyketsos+CG%22">Lyketsos CG</searchLink>; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA.; Johns Hopkins Alzheimer's Disease Research Center, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Mahairaki+V%22">Mahairaki V</searchLink>; Department of Genetic Medicine, Johns Hopkins School of Medicine, 21205, Baltimore, MD, USA. vmachai1@jhmi.edu.; The Richman Family Precision Medicine Center of Excellence in Alzheimer's Disease, Johns Hopkins School of Medicine, 21287, Baltimore, MD, USA. vmachai1@jhmi.edu.
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  Data: <searchLink fieldCode="JN" term="%229607835%22">Molecular psychiatry</searchLink> [Mol Psychiatry] 2024 Nov; Vol. 29 (11), pp. 3644-3652. <i>Date of Electronic Publication: </i>2024 Jun 05.
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              Text: 2024 Nov
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