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Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex.

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Title: Development of an improved blood-stage malaria vaccine targeting the essential RH5-CyRPA-RIPR invasion complex.
Authors: Williams BG; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., King LDW; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Pulido D; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Quinkert D; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Lias AM; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Silk SE; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Ragotte RJ; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Davies H; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Barrett JR; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., McHugh K; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Rigby CA; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK., Alanine DGW; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Barfod L; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Shea MW; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Cowley LA; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Dabbs RA; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Pattinson DJ; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Douglas AD; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Lyth OR; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Illingworth JJ; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Jin J; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Carnrot C; Novavax AB, Kungsgatan 109, SE-753 18, Uppsala, Sweden., Kotraiah V; Leidos Life Sciences, Frederick, MD, USA., Christen JM; Leidos Life Sciences, Frederick, MD, USA., Noe AR; Leidos Life Sciences, Frederick, MD, USA.; Latham BioPharm Group, Elkridge, MD, USA., MacGill RS; Center for Vaccine Innovation and Access, PATH, Washington, DC, USA., King CR; Center for Vaccine Innovation and Access, PATH, Washington, DC, USA., Birkett AJ; Center for Vaccine Innovation and Access, PATH, Washington, DC, USA., Soisson LA; USAID, 1300 Pennsylvania Ave. NW, Washington, DC, USA., Skinner K; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK., Miura K; Laboratory of Malaria and Vector Research, NIAID/NIH, Rockville, MD, USA., Long CA; Laboratory of Malaria and Vector Research, NIAID/NIH, Rockville, MD, USA., Higgins MK; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK., Draper SJ; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK. simon.draper@bioch.ox.ac.uk.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK. simon.draper@bioch.ox.ac.uk.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK. simon.draper@bioch.ox.ac.uk.; NIHR Oxford Biomedical Research Centre, Oxford, UK. simon.draper@bioch.ox.ac.uk.
Source: Nature communications [Nat Commun] 2024 Jun 07; Vol. 15 (1), pp. 4857. Date of Electronic Publication: 2024 Jun 07.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Lias+AM%22">Lias AM</searchLink>; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Silk+SE%22">Silk SE</searchLink>; Department of Biochemistry, University of Oxford, Dorothy Crowfoot Hodgkin Building, Oxford, UK.; Kavli Institute for Nanoscience Discovery, Dorothy Crowfoot Hodgkin Building, University of Oxford, Oxford, UK.; The Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Ragotte+RJ%22">Ragotte RJ</searchLink>; 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