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Impact of extended lung protection during mechanical ventilation on lung recovery in patients with COVID-19 ARDS: a phase II randomized controlled trial.

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Title: Impact of extended lung protection during mechanical ventilation on lung recovery in patients with COVID-19 ARDS: a phase II randomized controlled trial.
Authors: Costa ELV; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Research and Education Institute, Hospital Sírio-Libanes, Sao Paulo, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Alcala GC; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Tucci MR; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Goligher E; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.; Toronto General Hospital Research Institute, Toronto, Canada., Morais CC; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Departamento de Fisioterapia, Universidade Federal de Pernambuco, Recife, PE, Brazil., Dianti J; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.; Toronto General Hospital Research Institute, Toronto, Canada., Nakamura MAP; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil., Oliveira LB; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Pereira SM; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada., Toufen C Jr; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Barbas CSV; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.; Adult ICU Albert Einstein Hospital, São Paulo, Brazil., Carvalho CRR; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil., Amato MBP; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil. marcelo.amato@fm.usp.br.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil. marcelo.amato@fm.usp.br.
Source: Annals of intensive care [Ann Intensive Care] 2024 Jun 08; Vol. 14 (1), pp. 85. Date of Electronic Publication: 2024 Jun 08.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101562873 Publication Model: Electronic Cited Medium: Print ISSN: 2110-5820 (Print) Linking ISSN: 21105820 NLM ISO Abbreviation: Ann Intensive Care Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Impact of extended lung protection during mechanical ventilation on lung recovery in patients with COVID-19 ARDS: a phase II randomized controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Costa+ELV%22">Costa ELV</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Research and Education Institute, Hospital Sírio-Libanes, Sao Paulo, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Alcala+GC%22">Alcala GC</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Tucci+MR%22">Tucci MR</searchLink>; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Goligher+E%22">Goligher E</searchLink>; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.; Toronto General Hospital Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Morais+CC%22">Morais CC</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Departamento de Fisioterapia, Universidade Federal de Pernambuco, Recife, PE, Brazil.<br /><searchLink fieldCode="AU" term="%22Dianti+J%22">Dianti J</searchLink>; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.; Toronto General Hospital Research Institute, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Nakamura+MAP%22">Nakamura MAP</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.<br /><searchLink fieldCode="AU" term="%22Oliveira+LB%22">Oliveira LB</searchLink>; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Pereira+SM%22">Pereira SM</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Canada.; Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Canada.<br /><searchLink fieldCode="AU" term="%22Toufen+C+Jr%22">Toufen C Jr</searchLink>; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Barbas+CSV%22">Barbas CSV</searchLink>; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.; Adult ICU Albert Einstein Hospital, São Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+CRR%22">Carvalho CRR</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil.<br /><searchLink fieldCode="AU" term="%22Amato+MBP%22">Amato MBP</searchLink>; Laboratório de Pneumologia LIM-09, Faculdade de Medicina, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, 455 Dr Arnaldo Ave, Room 2144, São Paulo, SP, Brazil. marcelo.amato@fm.usp.br.; Divisao de Pneumologia, Faculdade de Medicina, Instituto do Coracao, Hospital das Clinicas HCFMUSP, Universidade de Sao Paulo, São Paulo, SP, Brasil. marcelo.amato@fm.usp.br.
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