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Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes.

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Title: Characterization of genetic variants of GIPR reveals a contribution of β-arrestin to metabolic phenotypes.
Authors: Kizilkaya HS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Sørensen KV; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Madsen JS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark., Lindquist P; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Douros JD; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA.; Indiana Biosciences Research Institute Indianapolis, Indianapolis, IN, USA., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Berghella A; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.; Department of Bioscience and Agro-Food and Environmental Technology, University of Teramo, Teramo, Italy., Gerlach PA; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gasbjerg LS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mokrosiński J; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA., Mowery SA; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA.; Indiana Biosciences Research Institute Indianapolis, Indianapolis, IN, USA., Knerr PJ; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA.; Indiana Biosciences Research Institute Indianapolis, Indianapolis, IN, USA., Finan B; Novo Nordisk Research Center Indianapolis, Indianapolis, IN, USA.; Eli Lilly and Company, Indianapolis, IN, USA., Campbell JE; Duke Molecular Physiology Institute, Duke University Durham, Durham, NC, USA., D'Alessio DA; Duke Molecular Physiology Institute, Duke University Durham, Durham, NC, USA., Perez-Tilve D; Department of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Faas F; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mathiasen S; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rungby J; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Herlev, Denmark., Sørensen HT; Department of Clinical Epidemiology, Aarhus University, Aarhus, Denmark.; Department of Epidemiology, Boston University, Boston, MA, USA., Vaag A; Steno Diabetes Center Copenhagen, Herlev, Denmark.; Department of Clinical Sciences, Lund University Diabetes Center, Lund University, Malmö, Sweden., Nielsen JS; Steno Diabetes Center Odense, Odense University Hospital, Odense, Denmark.; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Holm JC; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; The Children's Obesity Clinic, accredited European Centre for Obesity Management, Department of Pediatrics, Holbæk Hospital, Holbæk, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lauenborg J; Department of Obstetrics and Gynecology, Copenhagen University Hospital Herlev, Herlev, Denmark., Damm P; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Pregnant Women with Diabetes, Rigshospitalet, Copenhagen, Denmark.; Department of Obstetrics, Rigshospitalet, Copenhagen, Denmark., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Clinical Metabolic Research, Department of Medicine, Gentofte Hospital, Copenhagen, Denmark., Linneberg A; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Center for Clinical Research and Prevention, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark., Hartmann B; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Holst JJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Wright SC; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden., Lauschke VM; Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. niels.grarup@sund.ku.dk., Hauser AS; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark. alexander.hauser@sund.ku.dk., Rosenkilde MM; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. rosenkilde@sund.ku.dk.
Source: Nature metabolism [Nat Metab] 2024 Jul; Vol. 6 (7), pp. 1268-1281. Date of Electronic Publication: 2024 Jun 13.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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