Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.

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Title: Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.
Authors: Arefanian H; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al Madhoun A; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al-Rashed F; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Alzaid F; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Institut Necker Enfants Malades (INEM), French Institute of Health and Medical Research (INSERM), Immunity & Metabolism of Diabetes (IMMEDIAB), Université de Paris Cité, 75014 Paris, France., Bahman F; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Nizam R; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Alhusayan M; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait., John S; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Jacob S; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Williams MR; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abukhalaf N; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Shenouda S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Joseph S; Special Services Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait., AlSaeed H; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Kochumon S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Mohammad A; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Koti L; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Sindhu S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abu-Farha M; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Department of Translational Research, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abubaker J; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Thanaraj TA; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Ahmad R; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al-Mulla F; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Source: Cells [Cells] 2024 May 30; Vol. 13 (11). Date of Electronic Publication: 2024 May 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2073-4409
DOI:10.3390/cells13110949