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Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.

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Title: Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.
Authors: Arefanian H; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al Madhoun A; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al-Rashed F; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Alzaid F; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Institut Necker Enfants Malades (INEM), French Institute of Health and Medical Research (INSERM), Immunity & Metabolism of Diabetes (IMMEDIAB), Université de Paris Cité, 75014 Paris, France., Bahman F; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Nizam R; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Alhusayan M; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait., John S; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Jacob S; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Williams MR; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abukhalaf N; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Shenouda S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Joseph S; Special Services Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait., AlSaeed H; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Kochumon S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Mohammad A; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Koti L; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Sindhu S; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abu-Farha M; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Department of Translational Research, Dasman Diabetes Institute, Dasman 15462, Kuwait., Abubaker J; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Thanaraj TA; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait., Ahmad R; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait., Al-Mulla F; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.
Source: Cells [Cells] 2024 May 30; Vol. 13 (11). Date of Electronic Publication: 2024 May 30.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Unraveling Verapamil's Multidimensional Role in Diabetes Therapy: From β-Cell Regeneration to Cholecystokinin Induction in Zebrafish and MIN6 Cell-Line Models.
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  Data: <searchLink fieldCode="AU" term="%22Arefanian+H%22">Arefanian H</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Al+Madhoun+A%22">Al Madhoun A</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Al-Rashed+F%22">Al-Rashed F</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Alzaid+F%22">Alzaid F</searchLink>; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Institut Necker Enfants Malades (INEM), French Institute of Health and Medical Research (INSERM), Immunity & Metabolism of Diabetes (IMMEDIAB), Université de Paris Cité, 75014 Paris, France.<br /><searchLink fieldCode="AU" term="%22Bahman+F%22">Bahman F</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Nizam+R%22">Nizam R</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Alhusayan+M%22">Alhusayan M</searchLink>; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22John+S%22">John S</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Jacob+S%22">Jacob S</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Williams+MR%22">Williams MR</searchLink>; Department of Bioenergetics & Neurometabolism, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Abukhalaf+N%22">Abukhalaf N</searchLink>; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Shenouda+S%22">Shenouda S</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Joseph+S%22">Joseph S</searchLink>; Special Services Facilities, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22AlSaeed+H%22">AlSaeed H</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Kochumon+S%22">Kochumon S</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Mohammad+A%22">Mohammad A</searchLink>; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Koti+L%22">Koti L</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Sindhu+S%22">Sindhu S</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Animal and Imaging Core Facility, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Abu-Farha+M%22">Abu-Farha M</searchLink>; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait.; Department of Translational Research, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Abubaker+J%22">Abubaker J</searchLink>; Department of Biochemistry and Molecular Biology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Thanaraj+TA%22">Thanaraj TA</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Ahmad+R%22">Ahmad R</searchLink>; Department of Immunology & Microbiology, Dasman Diabetes Institute, Dasman 15462, Kuwait.<br /><searchLink fieldCode="AU" term="%22Al-Mulla+F%22">Al-Mulla F</searchLink>; Department of Genetics and Bioinformatics, Dasman Diabetes Institute, Dasman 15462, Kuwait.
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  Data: <searchLink fieldCode="JN" term="%22101600052%22">Cells</searchLink> [Cells] 2024 May 30; Vol. 13 (11). <i>Date of Electronic Publication: </i>2024 May 30.
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