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In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss.

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Title: In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss.
Authors: Vijayakumar S; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., DiGuiseppi JA; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Dabestani PJ; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Ryan WG; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA., Quevedo RV; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Li Y; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Diers J; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Tu S; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Fleegel J; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Nguyen C; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Rhoda LM; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Imami AS; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA., Hamoud AA; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA., Lovas S; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., McCullumsmith RE; Department of Neurosciences, University of Toledo, Toledo, OH 43614, USA.; Neurosciences Institute, ProMedica, Toledo, OH 43606, USA., Zallocchi M; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA., Zuo J; Department of Biomedical Sciences, School of Medicine, Creighton University, Omaha, NE 68178, USA.; Ting Therapeutics, 9310 Athena Circle, San Diego, CA 92037, USA.
Source: Science advances [Sci Adv] 2024 Jun 21; Vol. 10 (25), pp. eadk2299. Date of Electronic Publication: 2024 Jun 19.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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  Data: In silico transcriptome screens identify epidermal growth factor receptor inhibitors as therapeutics for noise-induced hearing loss.
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