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A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.

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Title: A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
Authors: Spriano F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Sartori G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Sgrignani J; Institute of Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona., Barnabei L; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Arribas AJ; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; SIB Swiss Institute of Bioinformatics, Lausanne., Guala M; Chimete, Tortona., Del Amor AMC; Department of Biomedical and Clinical Sciences, Cell Biology, Medical Faculty, Linköping University, Linköping., Tomasso MR; Drexel University, College of Medicine, Department of Biochemistry and Molecular Biology, Philadelphia, PA., Tarantelli C; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Cascione L; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; SIB Swiss Institute of Bioinformatics, Lausanne., Golino G; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; Department of Pharmacy, University of Napoli Federico II, Napoli., Riveiro ME; Early Drug Development Group, Boulogne-Billancourt., Bortolozzi R; Department of Woman's and Child's Health, University of Padova, Italy; Istituto di Ricerca Pediatrica IRP, Fondazione Città della Speranza, Padova., Lupia A; Department of Pharmacy, University of Napoli Federico II, Napoli, Italy; Net4science Srl, Magna Graecia University of Catanzaro, Catanzaro., Paduano F; University 'Magna Græcia' of Catanzaro, Catanzaro, Italy; Tecnologica Research Institute and Marrelli Health, Biomedical Section, Stem Cells and Medical Genetics Units, Crotone., Huguet S; Institut Curie, Paris., Rezai K; Institut Curie, Paris., Rinaldi A; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Margheriti F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Ventura P; Institute of Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona., Guarda G; Institute of Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona., Costa G; University 'Magna Græcia' of Catanzaro, Catanzaro., Rocca R; University 'Magna Græcia' of Catanzaro, Catanzaro., Furlan A; Institute of Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona., Verdonk LM; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Leiden., Innocenti P; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Leiden., Martin NI; Biological Chemistry Group, Institute of Biology Leiden, Leiden University, Leiden., Viola G; Department of Woman's and Child's Health, University of Padova, Italy; Istituto di Ricerca Pediatrica IRP, Fondazione Città della Speranza, Padova., Driessen C; Kantosspital St Gallen, St Gallen., Zucca E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona., Stathis A; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona., Gahtory D; BIMINI Biotech B.V., Leiden., Van den Nieuwboer M; BIMINI Biotech B.V., Leiden., Bornhauser B; Children's Hospital Zurich, Zurich., Alcaro S; University 'Magna Græcia' of Catanzaro, Catanzaro., Trapasso F; University 'Magna Græcia' of Catanzaro, Catanzaro., Cristobal S; Department of Biomedical and Clinical Sciences, Cell Biology, Medical Faculty, Linköping University, Linköping, Sweden; Ikerbasque, Basque Foundation for Sciences, Department of Department of Physiology, Faculty of Medicine and Nursing, University of the Basque Country., Padrick SB; Drexel University, College of Medicine, Department of Biochemistry and Molecular Biology, Philadelphia, PA., Pazzi N; Chimete, Tortona., Cavalli F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona., Cavalli A; Institute of Research in Biomedicine, Faculty of Biomedical Sciences, USI, Bellinzona., Gaudio E; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona. eugaudio1976@gmail.com., Bertoni F; Institute of Oncology Research, Faculty of Biomedical Sciences, USI, Bellinzona, Switzerland; Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona. francesco.bertoni@ior.usi.ch.
Source: Haematologica [Haematologica] 2024 Nov 01; Vol. 109 (11), pp. 3602-3614. Date of Electronic Publication: 2024 Nov 01.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Ferrata Storti Foundation Country of Publication: Italy NLM ID: 0417435 Publication Model: Electronic Cited Medium: Internet ISSN: 1592-8721 (Electronic) Linking ISSN: 03906078 NLM ISO Abbreviation: Haematologica Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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  Data: A first-in-class Wiskott-Aldrich syndrome protein activator with antitumor activity in hematologic cancers.
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