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Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies.

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Title: Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies.
Authors: Bryniarski MA; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA. Electronic address: mbryniar@amgen.com., Tuhin MTH; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Acker TM; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Wakefield DL; Research Biomics, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Sethaputra PG; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Cook KD; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Soto M; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA., Ponce M; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA., Primack R; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA., Jagarapu A; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., LaGory EL; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA., Conner KP; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA. Electronic address: kipc@amgen.com.
Source: Journal of pharmaceutical sciences [J Pharm Sci] 2024 Sep; Vol. 113 (9), pp. 2879-2894. Date of Electronic Publication: 2024 Jun 19.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 2985195R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6017 (Electronic) Linking ISSN: 00223549 NLM ISO Abbreviation: J Pharm Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Cellular Neonatal Fc Receptor Recycling Efficiencies can Differentiate Target-Independent Clearance Mechanisms of Monoclonal Antibodies.
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  Data: <searchLink fieldCode="AU" term="%22Bryniarski+MA%22">Bryniarski MA</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA. Electronic address: mbryniar@amgen.com.<br /><searchLink fieldCode="AU" term="%22Tuhin+MTH%22">Tuhin MTH</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Acker+TM%22">Acker TM</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Wakefield+DL%22">Wakefield DL</searchLink>; Research Biomics, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Sethaputra+PG%22">Sethaputra PG</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Cook+KD%22">Cook KD</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Soto+M%22">Soto M</searchLink>; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.<br /><searchLink fieldCode="AU" term="%22Ponce+M%22">Ponce M</searchLink>; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.<br /><searchLink fieldCode="AU" term="%22Primack+R%22">Primack R</searchLink>; Pharmacokinetics & Drug Metabolism, Amgen Research, One Amgen Center Drive, Thousand Oaks, CA 91320, USA.<br /><searchLink fieldCode="AU" term="%22Jagarapu+A%22">Jagarapu A</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22LaGory+EL%22">LaGory EL</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA.<br /><searchLink fieldCode="AU" term="%22Conner+KP%22">Conner KP</searchLink>; Pharmacokinetics and Drug Metabolism, Amgen Research, 750 Gateway Blvd, Suite 100, South San Francisco, CA 94080, USA. Electronic address: kipc@amgen.com.
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  Data: <searchLink fieldCode="JN" term="%222985195R%22">Journal of pharmaceutical sciences</searchLink> [J Pharm Sci] 2024 Sep; Vol. 113 (9), pp. 2879-2894. <i>Date of Electronic Publication: </i>2024 Jun 19.
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