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Structure-Metabolism Relationships of Benzimidazole Derivatives with anti-Trypanosoma cruzi Activity for Chagas Disease.

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Title: Structure-Metabolism Relationships of Benzimidazole Derivatives with anti-Trypanosoma cruzi Activity for Chagas Disease.
Authors: Espinoza-Chávez RM; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil., de Oliveira Rezende Júnior C; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil.; Institute of Chemistry, Federal University of Uberlândia (UFU), Uberlândia-MG, 38400-902, Brazil., Laureano de Souza M; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Consolin Chelucci R; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Michelan-Duarte S; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Krogh R; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Gomes Ferreira LL; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Valli M; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Sena de Oliveira A; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.; Department of Exact Sciences and Education, Federal University of Santa Catarina (UFSC), Blumenau-SC, 89036-004, Brazil., Andricopulo AD; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil., Carlos Dias L; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil.
Source: ChemMedChem [ChemMedChem] 2024 Oct 16; Vol. 19 (20), pp. e202400293. Date of Electronic Publication: 2024 Aug 27.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
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  Data: Structure-Metabolism Relationships of Benzimidazole Derivatives with anti-Trypanosoma cruzi Activity for Chagas Disease.
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  Data: <searchLink fieldCode="AU" term="%22Espinoza-Chávez+RM%22">Espinoza-Chávez RM</searchLink>; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Oliveira+Rezende+Júnior+C%22">de Oliveira Rezende Júnior C</searchLink>; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil.; Institute of Chemistry, Federal University of Uberlândia (UFU), Uberlândia-MG, 38400-902, Brazil.<br /><searchLink fieldCode="AU" term="%22Laureano+de+Souza+M%22">Laureano de Souza M</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Consolin+Chelucci+R%22">Consolin Chelucci R</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Michelan-Duarte+S%22">Michelan-Duarte S</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Krogh+R%22">Krogh R</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Gomes+Ferreira+LL%22">Gomes Ferreira LL</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Valli+M%22">Valli M</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Sena+de+Oliveira+A%22">Sena de Oliveira A</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.; Department of Exact Sciences and Education, Federal University of Santa Catarina (UFSC), Blumenau-SC, 89036-004, Brazil.<br /><searchLink fieldCode="AU" term="%22Andricopulo+AD%22">Andricopulo AD</searchLink>; Laboratory of Medicinal and Computational Chemistry, Physics Institute of Sao Carlos (IFSC), University of Sao Paulo (USP), Sao Carlos-SP, 13563-120, Brazil.<br /><searchLink fieldCode="AU" term="%22Carlos+Dias+L%22">Carlos Dias L</searchLink>; Laboratory of Synthetic Organic Chemistry, Institute of Chemistry, State University of Campinas (Unicamp), Campinas-SP, 13084-971, Brazil.
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