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Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment.

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Title: Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment.
Authors: Dammer EB; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA., Shantaraman A; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Ping L; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Duong DM; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA., Gerasimov ES; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Ravindran SP; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Gudmundsdottir V; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Frick EA; Icelandic Heart Association, 201 Kopavogur, Iceland., Gomez GT; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Walker KA; Laboratory of Behavioral Neuroscience, National Institute on Aging, Intramural Research Program, Baltimore, MD 21224, USA., Emilsson V; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Jennings LL; Novartis Biomedical Research, Cambridge, MA 02139, USA., Gudnason V; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland., Western D; Department of Psychiatry, Washington University, St. Louis, MO 63108, USA.; NeuroGenomics and Informatics, Washington University, St. Louis, MO 63108, USA., Cruchaga C; Department of Psychiatry, Washington University, St. Louis, MO 63108, USA.; NeuroGenomics and Informatics, Washington University, St. Louis, MO 63108, USA., Lah JJ; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Wingo TS; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA., Wingo AP; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Division of Mental Health, Atlanta VA Medical Center, Decatur, GA 30033, USA., Seyfried NT; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Levey AI; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA., Johnson ECB; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Source: Science translational medicine [Sci Transl Med] 2024 Jun 26; Vol. 16 (753), pp. eadn3504. Date of Electronic Publication: 2024 Jun 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE ε4 and atomoxetine treatment.
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  Data: <searchLink fieldCode="AU" term="%22Dammer+EB%22">Dammer EB</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Shantaraman+A%22">Shantaraman A</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Ping+L%22">Ping L</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Duong+DM%22">Duong DM</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Gerasimov+ES%22">Gerasimov ES</searchLink>; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Ravindran+SP%22">Ravindran SP</searchLink>; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Gudmundsdottir+V%22">Gudmundsdottir V</searchLink>; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Frick+EA%22">Frick EA</searchLink>; Icelandic Heart Association, 201 Kopavogur, Iceland.<br /><searchLink fieldCode="AU" term="%22Gomez+GT%22">Gomez GT</searchLink>; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.<br /><searchLink fieldCode="AU" term="%22Walker+KA%22">Walker KA</searchLink>; Laboratory of Behavioral Neuroscience, National Institute on Aging, Intramural Research Program, Baltimore, MD 21224, USA.<br /><searchLink fieldCode="AU" term="%22Emilsson+V%22">Emilsson V</searchLink>; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Jennings+LL%22">Jennings LL</searchLink>; Novartis Biomedical Research, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Gudnason+V%22">Gudnason V</searchLink>; Icelandic Heart Association, 201 Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, 101 Reykjavik, Iceland.<br /><searchLink fieldCode="AU" term="%22Western+D%22">Western D</searchLink>; Department of Psychiatry, Washington University, St. Louis, MO 63108, USA.; NeuroGenomics and Informatics, Washington University, St. Louis, MO 63108, USA.<br /><searchLink fieldCode="AU" term="%22Cruchaga+C%22">Cruchaga C</searchLink>; Department of Psychiatry, Washington University, St. Louis, MO 63108, USA.; NeuroGenomics and Informatics, Washington University, St. Louis, MO 63108, USA.<br /><searchLink fieldCode="AU" term="%22Lah+JJ%22">Lah JJ</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Wingo+TS%22">Wingo TS</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Wingo+AP%22">Wingo AP</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Division of Mental Health, Atlanta VA Medical Center, Decatur, GA 30033, USA.<br /><searchLink fieldCode="AU" term="%22Seyfried+NT%22">Seyfried NT</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Biochemistry, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Levey+AI%22">Levey AI</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+ECB%22">Johnson ECB</searchLink>; Goizueta Alzheimer's Disease Research Center, Emory University School of Medicine, Atlanta, GA 30322, USA.; Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2024 Jun 26; Vol. 16 (753), pp. eadn3504. <i>Date of Electronic Publication: </i>2024 Jun 26.
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