Identification of potent indolizine derivatives against Mycobacterial tuberculosis: In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies.
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| Title: | Identification of potent indolizine derivatives against Mycobacterial tuberculosis: In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies. |
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| Authors: | Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4000, South Africa. Electronic address: kvenugopala@kfu.edu.sa., Chandrashekharappa S; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R), Raebareli, Lucknow, UP 226002, India. Electronic address: c.sandeep@niperraebareli.edu.in., Deb PK; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology (BIT), Mesra, Ranchi 835215, Jharkhand, India. Electronic address: prankishoredeb@bitmesra.ac.in., Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan; Department of Pharmaceutical Sciences, College of Pharmacy, Qatar University, P.O. Box: 2713, Doha, Qatar., Pillay M; Department of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban 4001, South Africa., Tiwari P; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R), Raebareli, Lucknow, UP 226002, India., Chopra D; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal By-pass Road, Bhauri, Bhopal 462066, Madhya Pradesh, India., Borah P; Department of Biological Sciences and Bioengineering, Indian Institute of Technology (IIT), Kanpur, 208016, Uttar Pradesh, India., Tamhaev R; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France., Mourey L; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France., Lherbet C; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France., Aldhubiab BE; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia., Tratrat C; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia., Attimarad M; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia., Nair AB; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia., Sreeharsha N; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Pharmaceutics, Vidya Siri College of Pharmacy, Off Sarjapura Road, Bangalore 560035, India., Mailavaram RP; Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Samtanagar, Dhule 424 001, Maharashtra, India., Venugopala R; Department of Public Health Medicine, Howard College Campus, University of KwaZulu-Natal, Durban 4001, South Africa., Mohanlall V; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4000, South Africa., Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt. |
| Source: | International journal of biological macromolecules [Int J Biol Macromol] 2024 Aug; Vol. 274 (Pt 2), pp. 133285. Date of Electronic Publication: 2024 Jun 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38925196 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Identification of potent indolizine derivatives against Mycobacterial tuberculosis: In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Venugopala+KN%22">Venugopala KN</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4000, South Africa. Electronic address: kvenugopala@kfu.edu.sa.<br /><searchLink fieldCode="AU" term="%22Chandrashekharappa+S%22">Chandrashekharappa S</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R), Raebareli, Lucknow, UP 226002, India. Electronic address: c.sandeep@niperraebareli.edu.in.<br /><searchLink fieldCode="AU" term="%22Deb+PK%22">Deb PK</searchLink>; Department of Pharmaceutical Sciences and Technology, Birla Institute of Technology (BIT), Mesra, Ranchi 835215, Jharkhand, India. Electronic address: prankishoredeb@bitmesra.ac.in.<br /><searchLink fieldCode="AU" term="%22Al-Shar'i+NA%22">Al-Shar'i NA</searchLink>; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan; Department of Pharmaceutical Sciences, College of Pharmacy, Qatar University, P.O. Box: 2713, Doha, Qatar.<br /><searchLink fieldCode="AU" term="%22Pillay+M%22">Pillay M</searchLink>; Department of Microbiology, National Health Laboratory Services, KZN Academic Complex, Inkosi Albert Luthuli Central Hospital, Durban 4001, South Africa.<br /><searchLink fieldCode="AU" term="%22Tiwari+P%22">Tiwari P</searchLink>; Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER-R), Raebareli, Lucknow, UP 226002, India.<br /><searchLink fieldCode="AU" term="%22Chopra+D%22">Chopra D</searchLink>; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal By-pass Road, Bhauri, Bhopal 462066, Madhya Pradesh, India.<br /><searchLink fieldCode="AU" term="%22Borah+P%22">Borah P</searchLink>; Department of Biological Sciences and Bioengineering, Indian Institute of Technology (IIT), Kanpur, 208016, Uttar Pradesh, India.<br /><searchLink fieldCode="AU" term="%22Tamhaev+R%22">Tamhaev R</searchLink>; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Mourey+L%22">Mourey L</searchLink>; Institut de Pharmacologie et de Biologie Structurale (IPBS), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UPS), Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Lherbet+C%22">Lherbet C</searchLink>; Synthèse et Physico-Chimie de Molécules d'Intérêt Biologique (LSPCMIB), UMR 5068, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Aldhubiab+BE%22">Aldhubiab BE</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Tratrat+C%22">Tratrat C</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Attimarad+M%22">Attimarad M</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Nair+AB%22">Nair AB</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Sreeharsha+N%22">Sreeharsha N</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Pharmaceutics, Vidya Siri College of Pharmacy, Off Sarjapura Road, Bangalore 560035, India.<br /><searchLink fieldCode="AU" term="%22Mailavaram+RP%22">Mailavaram RP</searchLink>; Department of Pharmaceutical Chemistry, Shri Vile Parle Kelavani Mandal's Institute of Pharmacy, Samtanagar, Dhule 424 001, Maharashtra, India.<br /><searchLink fieldCode="AU" term="%22Venugopala+R%22">Venugopala R</searchLink>; Department of Public Health Medicine, Howard College Campus, University of KwaZulu-Natal, Durban 4001, South Africa.<br /><searchLink fieldCode="AU" term="%22Mohanlall+V%22">Mohanlall V</searchLink>; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4000, South Africa.<br /><searchLink fieldCode="AU" term="%22Morsy+MA%22">Morsy MA</searchLink>; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227909578%22">International journal of biological macromolecules</searchLink> [Int J Biol Macromol] 2024 Aug; Vol. 274 (Pt 2), pp. 133285. <i>Date of Electronic Publication: </i>2024 Jun 24. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>7909578 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0003 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201418130%22">01418130 </searchLink><i>NLM ISO Abbreviation: </i>Int J Biol Macromol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38925196 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ijbiomac.2024.133285 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 133285 Titles: – TitleFull: Identification of potent indolizine derivatives against Mycobacterial tuberculosis: In vitro anti-TB properties, in silico target validation, molecular docking and dynamics studies. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Venugopala KN – PersonEntity: Name: NameFull: Chandrashekharappa S – PersonEntity: Name: NameFull: Deb PK – PersonEntity: Name: NameFull: Al-Shar'i NA – PersonEntity: Name: NameFull: Pillay M – PersonEntity: Name: NameFull: Tiwari P – PersonEntity: Name: NameFull: Chopra D – PersonEntity: Name: NameFull: Borah P – PersonEntity: Name: NameFull: Tamhaev R – PersonEntity: Name: NameFull: Mourey L – PersonEntity: Name: NameFull: Lherbet C – PersonEntity: Name: NameFull: Aldhubiab BE – PersonEntity: Name: NameFull: Tratrat C – PersonEntity: Name: NameFull: Attimarad M – PersonEntity: Name: NameFull: Nair AB – PersonEntity: Name: NameFull: Sreeharsha N – PersonEntity: Name: NameFull: Mailavaram RP – PersonEntity: Name: NameFull: Venugopala R – PersonEntity: Name: NameFull: Mohanlall V – PersonEntity: Name: NameFull: Morsy MA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2024 Aug Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1879-0003 Numbering: – Type: volume Value: 274 – Type: issue Value: Pt 2 Titles: – TitleFull: International journal of biological macromolecules Type: main |
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