Sustained Inhibition of GABA-AT by OV329 Enhances Neuronal Inhibition and Prevents Development of Benzodiazepine Refractory Seizures.

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Title: Sustained Inhibition of GABA-AT by OV329 Enhances Neuronal Inhibition and Prevents Development of Benzodiazepine Refractory Seizures.
Authors: Colmers PLW; Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111., Arshad MN; Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111., Mukherjee J; Ovid Therapeutics, New York, New York 10001., Lin S; Ovid Therapeutics, New York, New York 10001., Ng SFJ; Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111., Sarmiere P; Ovid Therapeutics, New York, New York 10001., Davies PA; Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111., Moss SJ; Department of Neuroscience, Tufts University School of Medicine, Boston, Massachusetts 02111 stephen.moss@tufts.edu.; Department of Neuroscience, Physiology and Pharmacology, University College London, London WC1 6BT, United Kingdom.
Source: ENeuro [eNeuro] 2024 Jul 09; Vol. 11 (7). Date of Electronic Publication: 2024 Jul 09 (Print Publication: 2024).
Publication Type: Journal Article
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 101647362 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2373-2822 (Electronic) Linking ISSN: 23732822 NLM ISO Abbreviation: eNeuro Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2373-2822
DOI:10.1523/ENEURO.0137-24.2024