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Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes.

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Title: Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes.
Authors: Gurlo T; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States., Liu R; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States., Wang Z; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States., Hoang J; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States., Ryazantsev S; Electron Imaging Center, California Nano Systems Institute, University of California, Los Angeles, Los Angeles, California, United States., Daval M; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States., Butler AE; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States., Yang X; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States.; Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, United States., Blencowe M; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States.; Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, United States., Butler PC; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.
Source: Physiological genomics [Physiol Genomics] 2024 Sep 01; Vol. 56 (9), pp. 621-633. Date of Electronic Publication: 2024 Jul 01.
Publication Type: Journal Article
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 9815683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1531-2267 (Electronic) Linking ISSN: 10948341 NLM ISO Abbreviation: Physiol Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dysregulation of cholesterol homeostasis is an early signal of β-cell proteotoxicity characteristic of type 2 diabetes.
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  Data: <searchLink fieldCode="AU" term="%22Gurlo+T%22">Gurlo T</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Liu+R%22">Liu R</searchLink>; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Wang+Z%22">Wang Z</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Hoang+J%22">Hoang J</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Ryazantsev+S%22">Ryazantsev S</searchLink>; Electron Imaging Center, California Nano Systems Institute, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Daval+M%22">Daval M</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Butler+AE%22">Butler AE</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Yang+X%22">Yang X</searchLink>; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States.; Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Blencowe+M%22">Blencowe M</searchLink>; Department of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, California, United States.; Molecular, Cellular, and Integrative Physiology Interdepartmental Program, University of California, Los Angeles, Los Angeles, California, United States.<br /><searchLink fieldCode="AU" term="%22Butler+PC%22">Butler PC</searchLink>; Larry L. Hillblom Islet Research Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, United States.
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