Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge.
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| Title: | Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge. |
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| Authors: | Gasbjerg LS; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Rasmussen RS; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Dragan A; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Lindquist P; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Melchiorsen JU; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Stepniewski TM; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain.; InterAx Biotech AG, Villigen, Switzerland.; Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Warsaw, Poland., Schiellerup S; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Tordrup EK; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gadgaard S; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Bainan Biotech, Copenhagen, Denmark., Kizilkaya HS; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Willems S; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Zhong Y; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China., Wang Y; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, China.; National Key Laboratory of Chinese Medicine Modernization, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, China., Wright SC; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Lauschke VM; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany., Hartmann B; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Holst JJ; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Center for Basic Metabolic Research, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Selent J; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain., Rosenkilde MM; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2025 Jul; Vol. 182 (14), pp. 3353-3370. Date of Electronic Publication: 2024 Jul 01. |
| Publication Type: | Journal Article; Comparative Study |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 38952084 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gasbjerg+LS%22">Gasbjerg LS</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Rasmussen+RS%22">Rasmussen RS</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Dragan+A%22">Dragan A</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lindquist+P%22">Lindquist P</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Melchiorsen+JU%22">Melchiorsen JU</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Stepniewski+TM%22">Stepniewski TM</searchLink>; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain.; InterAx Biotech AG, Villigen, Switzerland.; Biological and Chemical Research Centre, Faculty of Chemistry, University of Warsaw, Warsaw, Poland.<br /><searchLink fieldCode="AU" term="%22Schiellerup+S%22">Schiellerup S</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Tordrup+EK%22">Tordrup EK</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Gadgaard+S%22">Gadgaard S</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Bainan Biotech, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kizilkaya+HS%22">Kizilkaya HS</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Willems+S%22">Willems S</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Zhong+Y%22">Zhong Y</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China.; Innovation Institute for Artificial Intelligence in Medicine of Zhejiang University, Hangzhou, China.; National Key Laboratory of Chinese Medicine Modernization, Innovation Center of Yangtze River Delta, Zhejiang University, Jiaxing, China.<br /><searchLink fieldCode="AU" term="%22Wright+SC%22">Wright SC</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.<br /><searchLink fieldCode="AU" term="%22Lauschke+VM%22">Lauschke VM</searchLink>; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.; Dr Margarete Fischer-Bosch Institute of Clinical Pharmacology, Stuttgart, Germany.; University of Tübingen, Tübingen, Germany.<br /><searchLink fieldCode="AU" term="%22Hartmann+B%22">Hartmann B</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Holst+JJ%22">Holst JJ</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Center for Basic Metabolic Research, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Selent+J%22">Selent J</searchLink>; Research Programme on Biomedical Informatics (GRIB), Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rosenkilde+MM%22">Rosenkilde MM</searchLink>; Department of Biomedical Sciences, Faculty of Healthy and Medical Sciences, University of Copenhagen, Copenhagen, Denmark. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2025 Jul; Vol. 182 (14), pp. 3353-3370. <i>Date of Electronic Publication: </i>2024 Jul 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Comparative Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=38952084 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1111/bph.16478 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 3353 Titles: – TitleFull: Altered desensitization and internalization patterns of rodent versus human glucose-dependent insulinotropic polypeptide (GIP) receptors. An important drug discovery challenge. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gasbjerg LS – PersonEntity: Name: NameFull: Rasmussen RS – PersonEntity: Name: NameFull: Dragan A – PersonEntity: Name: NameFull: Lindquist P – PersonEntity: Name: NameFull: Melchiorsen JU – PersonEntity: Name: NameFull: Stepniewski TM – PersonEntity: Name: NameFull: Schiellerup S – PersonEntity: Name: NameFull: Tordrup EK – PersonEntity: Name: NameFull: Gadgaard S – PersonEntity: Name: NameFull: Kizilkaya HS – PersonEntity: Name: NameFull: Willems S – PersonEntity: Name: NameFull: Zhong Y – PersonEntity: Name: NameFull: Wang Y – PersonEntity: Name: NameFull: Wright SC – PersonEntity: Name: NameFull: Lauschke VM – PersonEntity: Name: NameFull: Hartmann B – PersonEntity: Name: NameFull: Holst JJ – PersonEntity: Name: NameFull: Selent J – PersonEntity: Name: NameFull: Rosenkilde MM IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 07 Text: 2025 Jul Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1476-5381 Numbering: – Type: volume Value: 182 – Type: issue Value: 14 Titles: – TitleFull: British journal of pharmacology Type: main |
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