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Open-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma.

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Title: Open-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma.
Authors: Meyers PA; Memorial Sloan Kettering Cancer Center, New York, NY., Federman N; University of California Los Angeles, Los Angeles, CA., Daw N; The University of Texas MD Anderson Cancer Center, Houston, TX., Anderson PM; Cleveland Clinic Children's Hospital, Cleveland, OH., Davis LE; Oregon Health and Science University, Portland, OR., Kim A; Children's National Hospital, Washington, DC., Macy ME; University of Colorado School of Medicine and Children's Hospital Colorado, Denver, CO., Pietrofeso A; Oncternal Therapeutics, Inc, San Diego, CA., Ratan R; The University of Texas MD Anderson Cancer Center, Houston, TX., Riedel RF; Duke University Medical Center, Durham, NC., Trucco M; Cleveland Clinic Children's Hospital, Cleveland, OH., Breitmeyer JB; Oncternal Therapeutics, Inc, San Diego, CA., Toretsky JA; Georgetown University, Washington, DC., Ludwig JA; The University of Texas MD Anderson Cancer Center, Houston, TX.
Source: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Nov; Vol. 42 (31), pp. 3725-3734. Date of Electronic Publication: 2024 Jul 02.
Publication Type: Journal Article; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Open-Label, Multicenter, Phase I/II, First-in-Human Trial of TK216: A First-Generation EWS::FLI1 Fusion Protein Antagonist in Ewing Sarcoma.
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  Data: <searchLink fieldCode="AU" term="%22Meyers+PA%22">Meyers PA</searchLink>; Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Federman+N%22">Federman N</searchLink>; University of California Los Angeles, Los Angeles, CA.<br /><searchLink fieldCode="AU" term="%22Daw+N%22">Daw N</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Anderson+PM%22">Anderson PM</searchLink>; Cleveland Clinic Children's Hospital, Cleveland, OH.<br /><searchLink fieldCode="AU" term="%22Davis+LE%22">Davis LE</searchLink>; Oregon Health and Science University, Portland, OR.<br /><searchLink fieldCode="AU" term="%22Kim+A%22">Kim A</searchLink>; Children's National Hospital, Washington, DC.<br /><searchLink fieldCode="AU" term="%22Macy+ME%22">Macy ME</searchLink>; University of Colorado School of Medicine and Children's Hospital Colorado, Denver, CO.<br /><searchLink fieldCode="AU" term="%22Pietrofeso+A%22">Pietrofeso A</searchLink>; Oncternal Therapeutics, Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Ratan+R%22">Ratan R</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, TX.<br /><searchLink fieldCode="AU" term="%22Riedel+RF%22">Riedel RF</searchLink>; Duke University Medical Center, Durham, NC.<br /><searchLink fieldCode="AU" term="%22Trucco+M%22">Trucco M</searchLink>; Cleveland Clinic Children's Hospital, Cleveland, OH.<br /><searchLink fieldCode="AU" term="%22Breitmeyer+JB%22">Breitmeyer JB</searchLink>; Oncternal Therapeutics, Inc, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Toretsky+JA%22">Toretsky JA</searchLink>; Georgetown University, Washington, DC.<br /><searchLink fieldCode="AU" term="%22Ludwig+JA%22">Ludwig JA</searchLink>; The University of Texas MD Anderson Cancer Center, Houston, TX.
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  Data: <searchLink fieldCode="JN" term="%228309333%22">Journal of clinical oncology : official journal of the American Society of Clinical Oncology</searchLink> [J Clin Oncol] 2024 Nov; Vol. 42 (31), pp. 3725-3734. <i>Date of Electronic Publication: </i>2024 Jul 02.
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  Data: Journal Article; Clinical Trial, Phase I; Multicenter Study; Clinical Trial, Phase II; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8309333 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1527-7755 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220732183X%22">0732183X </searchLink><i>NLM ISO Abbreviation: </i>J Clin Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1200/JCO.24.00020
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              Text: 2024 Nov
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