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Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study.

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Title: Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study.
Authors: Armenteros JJA; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Brorsson C; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Johansen CH; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Banasik K; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Mazzoni G; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Moulder R; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland., Hirvonen K; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland., Suomi T; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland., Rasool O; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland., Bruggraber SFA; Department of Paediatrics, University of Cambridge, Cambridge, England., Marcovecchio ML; Department of Paediatrics, University of Cambridge, Cambridge, England., Hendricks E; Department of Paediatrics, University of Cambridge, Cambridge, England., Al-Sari N; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark., Mattila I; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark., Legido-Quigley C; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark., Suvitaival T; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark., Chmura PJ; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Knip M; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Pediatric Research Center, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland., Schulte AM; Bayer Pharmaceuticals, Berlin, Germany., Lee JH; Immunology & Inflammation Research Therapeutic Area, Sanofi, Massachusetts, USA., Sebastiani G; Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena, Siena, Italy.; Fondazione Umberto di Mario, ONLUS - Toscana Life Sciences, Siena, Italy., Grieco GE; Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena, Siena, Italy.; Fondazione Umberto di Mario, ONLUS - Toscana Life Sciences, Siena, Italy., Elo LL; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.; Institute of Biomedicine, University of Turku, Turku, Finland., Kaur S; Steno Diabetes Center Copenhagen, Herlev University Hospital, Herlev, Denmark., Pociot F; Steno Diabetes Center Copenhagen, Herlev University Hospital, Herlev, Denmark., Dotta F; Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena, Siena, Italy.; Tuscany Centre for Precision Medicine (CReMeP), Siena, Italy., Tree T; Department of Immunobiology, King's College, London, UK., Lahesmaa R; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland., Overbergh L; Department of Chronic Diseases and Metabolism, Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium., Mathieu C; Department of Chronic Diseases and Metabolism, Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium., Peakman M; Immunology & Inflammation Research Therapeutic Area, Sanofi, Massachusetts, USA.; Department of Immunobiology, King's College, London, UK., Brunak S; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Corporate Authors: INNODIA investigators
Source: Diabetes/metabolism research and reviews [Diabetes Metab Res Rev] 2024 Jul; Vol. 40 (5), pp. e3833.
Publication Type: Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 100883450 Publication Model: Print Cited Medium: Internet ISSN: 1520-7560 (Electronic) Linking ISSN: 15207552 NLM ISO Abbreviation: Diabetes Metab Res Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Multi-omics analysis reveals drivers of loss of β-cell function after newly diagnosed autoimmune type 1 diabetes: An INNODIA multicenter study.
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Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Hirvonen+K%22">Hirvonen K</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Suomi+T%22">Suomi T</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Rasool+O%22">Rasool O</searchLink>; Turku Bioscience Centre, University of Turku and Åbo Akademi University, Turku, Finland.; InFLAMES Research Flagship Center, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Bruggraber+SFA%22">Bruggraber SFA</searchLink>; Department of Paediatrics, University of Cambridge, Cambridge, England.<br /><searchLink fieldCode="AU" term="%22Marcovecchio+ML%22">Marcovecchio ML</searchLink>; Department of Paediatrics, University of Cambridge, Cambridge, England.<br /><searchLink fieldCode="AU" term="%22Hendricks+E%22">Hendricks E</searchLink>; Department of Paediatrics, University of Cambridge, Cambridge, England.<br /><searchLink fieldCode="AU" term="%22Al-Sari+N%22">Al-Sari N</searchLink>; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Mattila+I%22">Mattila I</searchLink>; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Legido-Quigley+C%22">Legido-Quigley C</searchLink>; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Suvitaival+T%22">Suvitaival T</searchLink>; Steno Diabetes Center Copenhagen, Systems Medicine, Herlev, Denmark.<br /><searchLink fieldCode="AU" term="%22Chmura+PJ%22">Chmura PJ</searchLink>; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Knip+M%22">Knip M</searchLink>; Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Pediatric Research Center, New Children's Hospital, Helsinki University Hospital, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Schulte+AM%22">Schulte AM</searchLink>; Bayer Pharmaceuticals, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Lee+JH%22">Lee JH</searchLink>; Immunology & Inflammation Research Therapeutic Area, Sanofi, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Sebastiani+G%22">Sebastiani G</searchLink>; Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena, Siena, Italy.; Fondazione Umberto di Mario, ONLUS - Toscana Life Sciences, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Grieco+GE%22">Grieco GE</searchLink>; Department of Medicine, Surgery and Neuroscience, Università degli Studi di Siena, Siena, Italy.; Fondazione Umberto di Mario, ONLUS - Toscana Life Sciences, Siena, Italy.<br /><searchLink fieldCode="AU" term="%22Elo+LL%22">Elo LL</searchLink>; 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InFLAMES Research Flagship Center, University of Turku, Turku, Finland.<br /><searchLink fieldCode="AU" term="%22Overbergh+L%22">Overbergh L</searchLink>; Department of Chronic Diseases and Metabolism, Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mathieu+C%22">Mathieu C</searchLink>; Department of Chronic Diseases and Metabolism, Endocrinology, Katholieke Universiteit Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Peakman+M%22">Peakman M</searchLink>; Immunology & Inflammation Research Therapeutic Area, Sanofi, Massachusetts, USA.; Department of Immunobiology, King's College, London, UK.<br /><searchLink fieldCode="AU" term="%22Brunak+S%22">Brunak S</searchLink>; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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