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Labetalol Dosing in Pregnancy: PBPK/PD and CYP2C19 Polymorphisms.

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Title: Labetalol Dosing in Pregnancy: PBPK/PD and CYP2C19 Polymorphisms.
Authors: Liu XI; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA., Green DJ; Office of Pediatric Therapeutics, US Food and Drug Administration, Silver Spring, MD, USA., van den Anker J; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA., Calderon J; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA., Ahmadzia H; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA., Burckart GJ; Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, MD, USA., Dallmann A; Bayer HealthCare SAS, Loos, France, on behalf of: Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer, AG, Germany.
Source: Journal of clinical pharmacology [J Clin Pharmacol] 2024 Nov; Vol. 64 (11), pp. 1443-1455. Date of Electronic Publication: 2024 Jul 08.
Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Labetalol Dosing in Pregnancy: PBPK/PD and CYP2C19 Polymorphisms.
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  Data: <searchLink fieldCode="AU" term="%22Liu+XI%22">Liu XI</searchLink>; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Green+DJ%22">Green DJ</searchLink>; Office of Pediatric Therapeutics, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22van+den+Anker+J%22">van den Anker J</searchLink>; Division of Clinical Pharmacology, Children's National Hospital, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Calderon+J%22">Calderon J</searchLink>; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Ahmadzia+H%22">Ahmadzia H</searchLink>; Division of Maternal-Fetal Medicine, Department of OB/Gyn, George Washington University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Burckart+GJ%22">Burckart GJ</searchLink>; Office of Clinical Pharmacology, US Food and Drug Administration, Silver Spring, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dallmann+A%22">Dallmann A</searchLink>; Bayer HealthCare SAS, Loos, France, on behalf of: Pharmacometrics/Modeling & Simulation, Research & Development, Pharmaceuticals, Bayer, AG, Germany.
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  Data: <searchLink fieldCode="JN" term="%220366372%22">Journal of clinical pharmacology</searchLink> [J Clin Pharmacol] 2024 Nov; Vol. 64 (11), pp. 1443-1455. <i>Date of Electronic Publication: </i>2024 Jul 08.
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        Value: 10.1002/jcph.2496
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              Text: 2024 Nov
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