Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors.
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| Title: | Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors. |
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| Authors: | Gerets HHJ; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Delaunois A; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Cardenas A; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Class R; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Fleurance R; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., de Haro T; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Laleu B; MMV Medicines for Malaria Venture, ICC, 1215 Geneva, Switzerland., Lowe MA; UK Branch of UCB Pharma, SL1 3WE Slough, United Kingdom., Rosseels ML; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium., Valentin JP; UCB Biopharma SRL, 1420 Braine-l'Alleud, Belgium. |
| Source: | Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2024 Oct 01; Vol. 201 (2), pp. 311-320. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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