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Machine-Learning-Guided Peptide Drug Discovery: Development of GLP-1 Receptor Agonists with Improved Drug Properties.

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Title: Machine-Learning-Guided Peptide Drug Discovery: Development of GLP-1 Receptor Agonists with Improved Drug Properties.
Authors: Nielsen JC; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Hjo Rringgaard C; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Nygaard MMR; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Wester A; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Elster L; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Porsgaard T; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Mikkelsen RB; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Rasmussen S; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Madsen AN; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Schlein M; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Vrang N; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Rigbolt K; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark., Dalbo Ge LS; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.
Source: Journal of medicinal chemistry [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 11814-11826. Date of Electronic Publication: 2024 Jul 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Machine-Learning-Guided Peptide Drug Discovery: Development of GLP-1 Receptor Agonists with Improved Drug Properties.
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  Data: <searchLink fieldCode="AU" term="%22Nielsen+JC%22">Nielsen JC</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Hjo+Rringgaard+C%22">Hjo Rringgaard C</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Nygaard+MMR%22">Nygaard MMR</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Wester+A%22">Wester A</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Elster+L%22">Elster L</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Porsgaard+T%22">Porsgaard T</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Mikkelsen+RB%22">Mikkelsen RB</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Rasmussen+S%22">Rasmussen S</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Madsen+AN%22">Madsen AN</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Schlein+M%22">Schlein M</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Vrang+N%22">Vrang N</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Rigbolt+K%22">Rigbolt K</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.<br /><searchLink fieldCode="AU" term="%22Dalbo+Ge+LS%22">Dalbo Ge LS</searchLink>; Gubra, Ho̷rsholm Kongevej 11B, Ho̷rsholm 2970, Denmark.
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  Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2024 Jul 25; Vol. 67 (14), pp. 11814-11826. <i>Date of Electronic Publication: </i>2024 Jul 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE
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        Value: 10.1021/acs.jmedchem.4c00417
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              Text: 2024 Jul 25
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