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Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells.

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Title: Targeting Unique Ligand Binding Domain Structural Features Downregulates DKK1 in Y537S ESR1 Mutant Breast Cancer Cells.
Authors: Young KS; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Hancock GR; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Fink E; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Zigrossi A; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Flowers B; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Cooper DA; Department of Chemistry, Illinois Institute of Technology, Chicago, IL 60616., Nguyen VT; Department of Chemistry, Illinois Institute of Technology, Chicago, IL 60616., Martinez M; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Mon KS; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Bosland M; Department of Pathology, University of Illinois Chicago, Chicago, IL 60607., Zak D; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Runde A; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Sharifi MN; Department of Medicine, University of Wisconsin, Madison, WI 53705., Kastrati I; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Minh DDL; Department of Chemistry, Illinois Institute of Technology, Chicago, IL 60616., Kregel S; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153., Fanning SW; Department of Cancer Biology, Loyola University Chicago Stritch School of Medicine, Maywood, IL 50153.
Source: Research square [Res Sq] 2024 Jun 25. Date of Electronic Publication: 2024 Jun 25.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101768035 Publication Model: Electronic Cited Medium: Internet ISSN: 2693-5015 (Electronic) Linking ISSN: 26935015 NLM ISO Abbreviation: Res Sq Subsets: PubMed not MEDLINE
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