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Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells.

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Title: Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells.
Authors: Ibrahim NS; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Sayed HA; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt., Sharaky M; Pharmacology unit, Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt., Diab HM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt., Elwahy AHM; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. aelwahy@cu.edu.eg., Abdelhamid IA; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. ismail_shafy@cu.edu.eg.
Source: Naunyn-Schmiedeberg's archives of pharmacology [Naunyn Schmiedebergs Arch Pharmacol] 2024 Dec; Vol. 397 (12), pp. 10091-10107. Date of Electronic Publication: 2024 Jul 09.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0326264 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1912 (Electronic) Linking ISSN: 00281298 NLM ISO Abbreviation: Naunyn Schmiedebergs Arch Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Synthesis, cytotoxicity, anti-inflammatory, anti-metastatic and anti-oxidant activities of novel chalcones incorporating 2-phenoxy-N-arylacetamide and thiophene moieties: induction of apoptosis in MCF7 and HEP2 cells.
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  Data: <searchLink fieldCode="AU" term="%22Ibrahim+NS%22">Ibrahim NS</searchLink>; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Sayed+HA%22">Sayed HA</searchLink>; Department of Chemistry (Biochemistry Division), Faculty of Science, Cairo University, Giza, 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Sharaky+M%22">Sharaky M</searchLink>; Pharmacology unit, Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt.<br /><searchLink fieldCode="AU" term="%22Diab+HM%22">Diab HM</searchLink>; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt.<br /><searchLink fieldCode="AU" term="%22Elwahy+AHM%22">Elwahy AHM</searchLink>; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. aelwahy@cu.edu.eg.<br /><searchLink fieldCode="AU" term="%22Abdelhamid+IA%22">Abdelhamid IA</searchLink>; Department of Chemistry, Faculty of Science, Cairo University, Giza, 12613, Egypt. ismail_shafy@cu.edu.eg.
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