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Itaconate is a metabolic regulator of bone formation in homeostasis and arthritis.

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Title: Itaconate is a metabolic regulator of bone formation in homeostasis and arthritis.
Authors: Kieler M; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Prammer LS; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria., Heller G; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria., Hofmann M; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Sperger S; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Hanetseder D; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Niederreiter B; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria., Komljenovic A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria., Klavins K; Institute of General Chemical Engineering, Riga Technical University, Riga, Latvia., Köcher T; Vienna BioCenter Core Facilities, Campus-Vienna-BioCenter 1, Vienna, Austria., Brunner JS; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA., Stanic I; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Oberbichler L; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Korosec A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria., Vogel A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Kerndl M; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Hromadová D; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Musiejovsky L; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Hajto A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Dobrijevic A; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria., Piwonka T; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria., Haschemi A; Department of Laboratory Medicine, Medical University of Vienna, Wien, Austria., Miller A; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria., Georgel P; INSERM UMR_S 1109, Fédération de Médecine Translationnelle (FMTS), Université de Strasbourg, Centre de Recherche en Immunologie et Hématologie, 1 Place de l'Hôpital, Strasbourg Cedex, France., Marolt Presen D; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria., Grillari J; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.; Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria., Hayer S; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria., Auger JP; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Krönke G; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany., Sharif O; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria., Aletaha D; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria., Schabbauer G; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria., Blüml S; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria stephan.blueml@meduniwien.ac.at.
Source: Annals of the rheumatic diseases [Ann Rheum Dis] 2024 Oct 21; Vol. 83 (11), pp. 1465-1479. Date of Electronic Publication: 2024 Oct 21.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 0372355 Publication Model: Electronic Cited Medium: Internet ISSN: 1468-2060 (Electronic) Linking ISSN: 00034967 NLM ISO Abbreviation: Ann Rheum Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Kieler+M%22">Kieler M</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Prammer+LS%22">Prammer LS</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Heller+G%22">Heller G</searchLink>; Department of Medicine I, Division of Oncology, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hofmann+M%22">Hofmann M</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Sperger+S%22">Sperger S</searchLink>; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hanetseder+D%22">Hanetseder D</searchLink>; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Niederreiter+B%22">Niederreiter B</searchLink>; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Komljenovic+A%22">Komljenovic A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Klavins+K%22">Klavins K</searchLink>; Institute of General Chemical Engineering, Riga Technical University, Riga, Latvia.<br /><searchLink fieldCode="AU" term="%22Köcher+T%22">Köcher T</searchLink>; Vienna BioCenter Core Facilities, Campus-Vienna-BioCenter 1, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Brunner+JS%22">Brunner JS</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Cell Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Stanic+I%22">Stanic I</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Oberbichler+L%22">Oberbichler L</searchLink>; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Korosec+A%22">Korosec A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Vogel+A%22">Vogel A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Kerndl+M%22">Kerndl M</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hromadová+D%22">Hromadová D</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Musiejovsky+L%22">Musiejovsky L</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hajto+A%22">Hajto A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Dobrijevic+A%22">Dobrijevic A</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Piwonka+T%22">Piwonka T</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Haschemi+A%22">Haschemi A</searchLink>; Department of Laboratory Medicine, Medical University of Vienna, Wien, Austria.<br /><searchLink fieldCode="AU" term="%22Miller+A%22">Miller A</searchLink>; Center for Pathobiochemistry and Genetics, Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Georgel+P%22">Georgel P</searchLink>; INSERM UMR_S 1109, Fédération de Médecine Translationnelle (FMTS), Université de Strasbourg, Centre de Recherche en Immunologie et Hématologie, 1 Place de l'Hôpital, Strasbourg Cedex, France.<br /><searchLink fieldCode="AU" term="%22Marolt+Presen+D%22">Marolt Presen D</searchLink>; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Grillari+J%22">Grillari J</searchLink>; Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Wien, Vienna, Austria.; Austrian Cluster for Tissue Regeneration, Vienna, Austria.; Institute of Molecular Biotechnology, University of Natural Resources and Life Sciences, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Hayer+S%22">Hayer S</searchLink>; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Auger+JP%22">Auger JP</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Krönke+G%22">Krönke G</searchLink>; Department of Internal Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nürnberg and Universitätsklinikum Erlangen, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Sharif+O%22">Sharif O</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Immunometabolism and Systems Biology of Obesity-Related Diseases (InSpiReD), Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Aletaha+D%22">Aletaha D</searchLink>; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Schabbauer+G%22">Schabbauer G</searchLink>; Institute for Vascular Biology, Centre for Physiology and Pharmacology, Medical University of Vienna, Wien, Vienna, Austria.; Christian Doppler Laboratory for Arginine Metabolism in Rheumatoid Arthritis and Multiple Sclerosis, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Blüml+S%22">Blüml S</searchLink>; Department of Rheumatology, Medical University of Vienna, Wien, Vienna, Austria stephan.blueml@meduniwien.ac.at.
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  Data: <searchLink fieldCode="JN" term="%220372355%22">Annals of the rheumatic diseases</searchLink> [Ann Rheum Dis] 2024 Oct 21; Vol. 83 (11), pp. 1465-1479. <i>Date of Electronic Publication: </i>2024 Oct 21.
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