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Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.

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Title: Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.
Authors: Lei KC; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany., Srinivas N; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany., Chandra M; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany., Kervarrec T; Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Tours, France., Coyaud E; Department of Biology, University Lille, INSERM, Protéomique Réponse Inflammatoire Spectrométrie de Masse (PRISM), Lille, France., Spassova I; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany., Peiffer L; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany., Houben R; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany., Shuda M; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Hoffmann D; Bioinformatics and Computational Biophysics, Faculty of Biology, University of Duisburg-Essen, Essen, Germany., Schrama D; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany., Becker JC; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany.
Source: Journal of medical virology [J Med Virol] 2024 Jul; Vol. 96 (7), pp. e29789.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Merkel cell polyomavirus pan-T antigen knockdown reduces cancer cell stemness and promotes neural differentiation independent of RB1.
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  Data: <searchLink fieldCode="AU" term="%22Lei+KC%22">Lei KC</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Srinivas+N%22">Srinivas N</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Chandra+M%22">Chandra M</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Kervarrec+T%22">Kervarrec T</searchLink>; Department of Pathology, Université de Tours, Centre Hospitalier Universitaire de Tours, Tours, France.<br /><searchLink fieldCode="AU" term="%22Coyaud+E%22">Coyaud E</searchLink>; Department of Biology, University Lille, INSERM, Protéomique Réponse Inflammatoire Spectrométrie de Masse (PRISM), Lille, France.<br /><searchLink fieldCode="AU" term="%22Spassova+I%22">Spassova I</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Peiffer+L%22">Peiffer L</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Houben+R%22">Houben R</searchLink>; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Shuda+M%22">Shuda M</searchLink>; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Hoffmann+D%22">Hoffmann D</searchLink>; Bioinformatics and Computational Biophysics, Faculty of Biology, University of Duisburg-Essen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Schrama+D%22">Schrama D</searchLink>; Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.<br /><searchLink fieldCode="AU" term="%22Becker+JC%22">Becker JC</searchLink>; German Cancer Research Centre (DKFZ), Heidelberg, Germany.; Translational Skin Cancer Research, German Cancer Consortium (DKTK), Heidelberg, Germany.; Department of Dermatology, University Hospital Essen, Essen, Germany.
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              Text: 2024 Jul
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