Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate.
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| Title: | Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate. |
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| Authors: | Bernardo LB; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. leandro.braga@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. leandro.braga@ime.eb.br., Borges CVN; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil., Buitrago PAG; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil., Kuča K; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic., Cavalcante SFA; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil., Sousa RB; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil., Lima ALS; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. santoslima@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. santoslima@ime.eb.br., Kitagawa DAS; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. kitagawa.daniel@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. kitagawa.daniel@ime.eb.br. |
| Source: | Archives of toxicology [Arch Toxicol] 2024 Oct; Vol. 98 (10), pp. 3397-3407. Date of Electronic Publication: 2024 Jul 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 39004640 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bernardo+LB%22">Bernardo LB</searchLink>; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. leandro.braga@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. leandro.braga@ime.eb.br.<br /><searchLink fieldCode="AU" term="%22Borges+CVN%22">Borges CVN</searchLink>; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil.<br /><searchLink fieldCode="AU" term="%22Buitrago+PAG%22">Buitrago PAG</searchLink>; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil.<br /><searchLink fieldCode="AU" term="%22Kuča+K%22">Kuča K</searchLink>; Department of Chemistry, Faculty of Science, University of Hradec Kralove, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Cavalcante+SFA%22">Cavalcante SFA</searchLink>; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil.<br /><searchLink fieldCode="AU" term="%22Sousa+RB%22">Sousa RB</searchLink>; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil.<br /><searchLink fieldCode="AU" term="%22Lima+ALS%22">Lima ALS</searchLink>; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. santoslima@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. santoslima@ime.eb.br.<br /><searchLink fieldCode="AU" term="%22Kitagawa+DAS%22">Kitagawa DAS</searchLink>; Instituto Militar de Engenharia (IME), Praça General Tibúrcio 80, Rio de Janeiro, RJ, 22290-270, Brazil. kitagawa.daniel@ime.eb.br.; Instituto de Defesa Química, Biológica, Radiológica e Nuclear (IDQBRN), Centro Tecnológico do Exército (CTEx), Avenida das Américas 28705, Área 4, Rio de Janeiro, RJ, 23020-470, Brazil. kitagawa.daniel@ime.eb.br. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220417615%22">Archives of toxicology</searchLink> [Arch Toxicol] 2024 Oct; Vol. 98 (10), pp. 3397-3407. <i>Date of Electronic Publication: </i>2024 Jul 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer-Verlag%22">Springer-Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0417615 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0738 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203405761%22">03405761 </searchLink><i>NLM ISO Abbreviation: </i>Arch Toxicol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=39004640 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00204-024-03821-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 3397 Titles: – TitleFull: Synthesis and in vitro assessment of the reactivation profile of clinically available oximes on the acetylcholinesterase model inhibited by A-230 nerve agent surrogate. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bernardo LB – PersonEntity: Name: NameFull: Borges CVN – PersonEntity: Name: NameFull: Buitrago PAG – PersonEntity: Name: NameFull: Kuča K – PersonEntity: Name: NameFull: Cavalcante SFA – PersonEntity: Name: NameFull: Sousa RB – PersonEntity: Name: NameFull: Lima ALS – PersonEntity: Name: NameFull: Kitagawa DAS IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: 2024 Oct Type: published Y: 2024 Identifiers: – Type: issn-electronic Value: 1432-0738 Numbering: – Type: volume Value: 98 – Type: issue Value: 10 Titles: – TitleFull: Archives of toxicology Type: main |
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