A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration.

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Title: A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regeneration.
Authors: Emmerich K; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Hageter J; Department of Biology, West Virginia University, Morgantown, WV 26505, USA., Hoang T; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Ophthalmology and Visual Sciences, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA.; Department of Cell and Developmental Biology, University of Michigan School of Medicine, Ann Arbor, MI 48105, USA., Lyu P; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Sharrock AV; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Ceisel A; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Thierer J; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Chunawala Z; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Nimmagadda S; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Palazzo I; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Matthews F; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Zhang L; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., White DT; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Rodriguez C; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Graziano G; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Marcos P; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., May A; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Mulligan T; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Reibman B; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Saxena MT; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Ackerley DF; School of Biological Sciences, Victoria University of Wellington, Wellington 6012, New Zealand., Qian J; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Blackshaw S; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Horstick E; Department of Biology, West Virginia University, Morgantown, WV 26505, USA.; Department of Neuroscience, West Virginia University, Morgantown, WV 26506, USA., Mumm JS; Wilmer Eye Institute and the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; McKusick-Nathans Institute and the Department of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.; Center for Nanomedicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA.
Source: Development (Cambridge, England) [Development] 2024 Aug 01; Vol. 151 (15). Date of Electronic Publication: 2024 Aug 12.
Publication Type: Journal Article
Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1477-9129
DOI:10.1242/dev.202754