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Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.

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Title: Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
Authors: Porter JC; UCL Respiratory, University College London, London, United Kingdom.; University College London Hospitals NHS Trust, London, United Kingdom., Inshaw J; Exploristics, Belfast, Ireland., Solis VJ; University College London Hospitals NHS Trust, London, United Kingdom., Denneny E; UCL Respiratory, University College London, London, United Kingdom.; University College London Hospitals NHS Trust, London, United Kingdom., Evans R; University College London Hospitals NHS Trust, London, United Kingdom., Temkin MI; Antimicrobial Defence Lab, The Francis Crick Institute, London, United Kingdom., De Vasconcelos N; Antimicrobial Defence Lab, The Francis Crick Institute, London, United Kingdom., Aramburu IV; Antimicrobial Defence Lab, The Francis Crick Institute, London, United Kingdom., Hoving D; Antimicrobial Defence Lab, The Francis Crick Institute, London, United Kingdom., Basire D; UCL Respiratory, University College London, London, United Kingdom., Crissell T; University College London Hospitals NHS Trust, London, United Kingdom., Guinto J; University College London Hospitals NHS Trust, London, United Kingdom., Webb A; University College London Hospitals NHS Trust, London, United Kingdom., Esmail H; University College London Hospitals NHS Trust, London, United Kingdom.; National Institute for Health Research, University College London Hospital Biomedical Research Centre, London, United Kingdom., Johnston V; University College London Hospitals NHS Trust, London, United Kingdom.; National Institute for Health Research, University College London Hospital Biomedical Research Centre, London, United Kingdom., Last A; University College London Hospitals NHS Trust, London, United Kingdom.; Clinical Research Department, London School of Hygiene and Tropical Medicine, London, United Kingdom., Rampling T; University College London Hospitals NHS Trust, London, United Kingdom.; National Institute for Health Research, University College London Hospital Biomedical Research Centre, London, United Kingdom., Lippert L; Charité - Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany., Helbig ET; Charité - Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany., Kurth F; Charité - Universitätsmedizin Berlin, Department of Infectious Diseases and Respiratory Medicine, Berlin, Germany., Williams B; University College London Hospitals NHS Trust, London, United Kingdom.; National Institute for Health Research, University College London Hospital Biomedical Research Centre, London, United Kingdom., Flynn A; Exploristics, Belfast, Ireland., Lukey PT; Target to Treatment Consulting Ltd, Stevenage, United Kingdom., Birault V; Translation, The Francis Crick Institute, London, United Kingdom., Papayannopoulos V; Antimicrobial Defence Lab, The Francis Crick Institute, London, United Kingdom.
Source: ELife [Elife] 2024 Jul 16; Vol. 12. Date of Electronic Publication: 2024 Jul 16.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE
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  Data: Anti-inflammatory therapy with nebulized dornase alfa for severe COVID-19 pneumonia: a randomized unblinded trial.
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  Data: <searchLink fieldCode="JN" term="%22101579614%22">ELife</searchLink> [Elife] 2024 Jul 16; Vol. 12. <i>Date of Electronic Publication: </i>2024 Jul 16.
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