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The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.

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Title: The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.
Authors: Chan V; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Camardi C; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Zhang K; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Orofiamma LA; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Anderson KE; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom., Hoque J; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Bone LN; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Awadeh Y; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Lee DKC; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada., Fu NJ; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada., Chow JTS; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada., Salmena L; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada., Stephens LR; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom., Hawkins PT; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom., Antonescu CN; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada., Botelho RJ; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.
Source: Molecular biology of the cell [Mol Biol Cell] 2024 Sep 01; Vol. 35 (9), pp. ar118. Date of Electronic Publication: 2024 Jul 18.
Publication Type: Journal Article
Journal Info: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE
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  Data: The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.
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  Data: <searchLink fieldCode="AU" term="%22Chan+V%22">Chan V</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Camardi+C%22">Camardi C</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Zhang+K%22">Zhang K</searchLink>; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Orofiamma+LA%22">Orofiamma LA</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Anderson+KE%22">Anderson KE</searchLink>; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hoque+J%22">Hoque J</searchLink>; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Bone+LN%22">Bone LN</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Awadeh+Y%22">Awadeh Y</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+DKC%22">Lee DKC</searchLink>; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Fu+NJ%22">Fu NJ</searchLink>; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Chow+JTS%22">Chow JTS</searchLink>; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Salmena+L%22">Salmena L</searchLink>; Department of Pharmacology & Toxicology, University of Toronto, Toronto, Ontario M5S1A8, Canada.<br /><searchLink fieldCode="AU" term="%22Stephens+LR%22">Stephens LR</searchLink>; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hawkins+PT%22">Hawkins PT</searchLink>; Signalling Programme, Babraham Institute, Cambridge CB22 4AT, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Antonescu+CN%22">Antonescu CN</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.<br /><searchLink fieldCode="AU" term="%22Botelho+RJ%22">Botelho RJ</searchLink>; Molecular Science Graduate Program, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, Ontario M5B2K3, Canada.
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  Data: <searchLink fieldCode="JN" term="%229201390%22">Molecular biology of the cell</searchLink> [Mol Biol Cell] 2024 Sep 01; Vol. 35 (9), pp. ar118. <i>Date of Electronic Publication: </i>2024 Jul 18.
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        Value: 10.1091/mbc.E23-09-0361
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      – TitleFull: The LCLAT1/LYCAT acyltransferase is required for EGF-mediated phosphatidylinositol-3,4,5-trisphosphate generation and Akt signaling.
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