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Development of covalent chemogenetic K2P channel activators.

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Title: Development of covalent chemogenetic K2P channel activators.
Authors: Deal PE; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Lee H; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Mondal A; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Lolicato M; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Mendonça PRF; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Black H; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA., Jang S; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA., El-Hilali X; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Bryant C; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA., Isacoff EY; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Weill Neurohub, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA., Renslo AR; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA. Electronic address: adam.renslo@ucsf.edu., Minor DL Jr; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA; Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 93858-2330, USA; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 93858-2330, USA. Electronic address: daniel.minor@ucsf.edu.
Source: Cell chemical biology [Cell Chem Biol] 2024 Jul 18; Vol. 31 (7), pp. 1305-1323.e9.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of covalent chemogenetic K<subscript>2P</subscript> channel activators.
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  Data: <searchLink fieldCode="AU" term="%22Deal+PE%22">Deal PE</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Lee+H%22">Lee H</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Mondal+A%22">Mondal A</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Lolicato+M%22">Lolicato M</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Mendonça+PRF%22">Mendonça PRF</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Black+H%22">Black H</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.<br /><searchLink fieldCode="AU" term="%22Jang+S%22">Jang S</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22El-Hilali+X%22">El-Hilali X</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Bryant+C%22">Bryant C</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA.<br /><searchLink fieldCode="AU" term="%22Isacoff+EY%22">Isacoff EY</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, CA 94720, USA; Weill Neurohub, University of California, Berkeley, Berkeley, CA 94720, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA.<br /><searchLink fieldCode="AU" term="%22Renslo+AR%22">Renslo AR</searchLink>; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 93858-2330, USA. Electronic address: adam.renslo@ucsf.edu.<br /><searchLink fieldCode="AU" term="%22Minor+DL+Jr%22">Minor DL Jr</searchLink>; Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Molecular Biophysics and Integrated Bio-imaging Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720 USA; Departments of Biochemistry and Biophysics, and Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 93858-2330, USA; California Institute for Quantitative Biomedical Research, University of California, San Francisco, San Francisco, CA 93858-2330, USA; Kavli Institute for Fundamental Neuroscience, University of California, San Francisco, San Francisco, CA 93858-2330, USA. Electronic address: daniel.minor@ucsf.edu.
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              Text: 2024 Jul 18
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