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An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial.

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Title: An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial.
Authors: Ortiz O; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain., Daca-Alvarez M; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain., Rivero-Sanchez L; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain., Gimeno-Garcia AZ; Hospital Universitario de Canarias, Digestive System Service, Santa Cruz de Tenerife, Spain., Carrillo-Palau M; Hospital Universitario de Canarias, Digestive System Service, Santa Cruz de Tenerife, Spain., Alvarez V; Complejo Hospitalario de Pontevedra, Department of Gastroenterology, Pontevedra, Spain., Ledo-Rodriguez A; Complejo Hospitalario de Pontevedra, Department of Gastroenterology, Pontevedra, Spain., Ricciardiello L; IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Gastroenterology, Hepatology, and Nutrition, University of Texas at MD Anderson Cancer Center, Houston, TX, USA., Pierantoni C; IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy., Hüneburg R; Department of Internal Medicine I and National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany; European Reference Network for Genetic Tumor Risk Syndromes (ERN Genturis), Bonn, Germany., Nattermann J; Department of Internal Medicine I and National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany; European Reference Network for Genetic Tumor Risk Syndromes (ERN Genturis), Bonn, Germany., Bisschops R; Gastroenterology Department, University Hospital Leuven, Leuven, Belgium., Tejpar S; Gastroenterology Department, University Hospital Leuven, Leuven, Belgium., Huerta A; Hospital Galdakao-Usansolo, Department of Gastroenterology, Galdakao, Spain., Riu Pons F; Gastroenterology Department, Hospital del Mar Research Institute, Barcelona, Spain., Alvarez-Urturi C; Gastroenterology Department, Hospital del Mar Research Institute, Barcelona, Spain., López-Vicente J; Hospital Universitario de Móstoles, Digestive System Service, Móstoles, Spain., Repici A; Gastroenterology Department, IRCCS Humanitas Research Hospital, Milan, Italy., Hassan C; Gastroenterology Department, IRCCS Humanitas Research Hospital, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Cid L; Hospital Alvaro Cunqueiro, Galicia, Spain; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain., Cavestro GM; Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy., Romero-Mascarell C; Hospital de la Santa Creu i Sant Pau, Gastroenterology Unit, Barcelona, Spain., Gordillo J; Hospital de la Santa Creu i Sant Pau, Gastroenterology Unit, Barcelona, Spain., Puig I; Institut de Recerca i Innovació en Ciències de la Vida i de la Salut a la Catalunya Central (IRIS-CC), Vic, Spain; Digestive Diseases Department, Althaia Xarxa Assistencial Universitària de Manresa, Manresa, Spain; Facultat de Medicina, Universitat de Vic-Central de Cataluña (UVIC-UCC), Vic, Spain., Herraiz M; University of Navarra Clinic-IdiSNA, Gastroenterology Department, Pamplona, Spain., Betes M; University of Navarra Clinic-IdiSNA, Gastroenterology Department, Pamplona, Spain., Herrero J; Complexo Hospitalario Universitario de Ourense, Instituto de Investigación Biomédica Galicia Sur, CIBERehd, Ourense, Spain., Jover R; Hospital Universitario de Alicante, Pais Valencia, Spain., Balaguer F; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain; University of Barcelona, Barcelona, Spain., Pellisé M; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address: mpellise@clinic.cat.
Corporate Authors: TIMELY study group
Source: The lancet. Gastroenterology & hepatology [Lancet Gastroenterol Hepatol] 2024 Sep; Vol. 9 (9), pp. 802-810. Date of Electronic Publication: 2024 Jul 19.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101690683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2468-1253 (Electronic) NLM ISO Abbreviation: Lancet Gastroenterol Hepatol Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: An artificial intelligence-assisted system versus white light endoscopy alone for adenoma detection in individuals with Lynch syndrome (TIMELY): an international, multicentre, randomised controlled trial.
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  Data: <searchLink fieldCode="AU" term="%22Ortiz+O%22">Ortiz O</searchLink>; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Daca-Alvarez+M%22">Daca-Alvarez M</searchLink>; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Rivero-Sanchez+L%22">Rivero-Sanchez L</searchLink>; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gimeno-Garcia+AZ%22">Gimeno-Garcia AZ</searchLink>; Hospital Universitario de Canarias, Digestive System Service, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Carrillo-Palau+M%22">Carrillo-Palau M</searchLink>; Hospital Universitario de Canarias, Digestive System Service, Santa Cruz de Tenerife, Spain.<br /><searchLink fieldCode="AU" term="%22Alvarez+V%22">Alvarez V</searchLink>; Complejo Hospitalario de Pontevedra, Department of Gastroenterology, Pontevedra, Spain.<br /><searchLink fieldCode="AU" term="%22Ledo-Rodriguez+A%22">Ledo-Rodriguez A</searchLink>; Complejo Hospitalario de Pontevedra, Department of Gastroenterology, Pontevedra, Spain.<br /><searchLink fieldCode="AU" term="%22Ricciardiello+L%22">Ricciardiello L</searchLink>; IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy; Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy; Gastroenterology, Hepatology, and Nutrition, University of Texas at MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Pierantoni+C%22">Pierantoni C</searchLink>; IRCCS Azienda Ospedaliero Universitaria di Bologna, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Hüneburg+R%22">Hüneburg R</searchLink>; Department of Internal Medicine I and National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany; European Reference Network for Genetic Tumor Risk Syndromes (ERN Genturis), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Nattermann+J%22">Nattermann J</searchLink>; Department of Internal Medicine I and National Center for Hereditary Tumor Syndromes, University Hospital Bonn, Bonn, Germany; European Reference Network for Genetic Tumor Risk Syndromes (ERN Genturis), Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Bisschops+R%22">Bisschops R</searchLink>; Gastroenterology Department, University Hospital Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Tejpar+S%22">Tejpar S</searchLink>; Gastroenterology Department, University Hospital Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Huerta+A%22">Huerta A</searchLink>; Hospital Galdakao-Usansolo, Department of Gastroenterology, Galdakao, Spain.<br /><searchLink fieldCode="AU" term="%22Riu+Pons+F%22">Riu Pons F</searchLink>; Gastroenterology Department, Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Alvarez-Urturi+C%22">Alvarez-Urturi C</searchLink>; Gastroenterology Department, Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22López-Vicente+J%22">López-Vicente J</searchLink>; Hospital Universitario de Móstoles, Digestive System Service, Móstoles, Spain.<br /><searchLink fieldCode="AU" term="%22Repici+A%22">Repici A</searchLink>; Gastroenterology Department, IRCCS Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Hassan+C%22">Hassan C</searchLink>; Gastroenterology Department, IRCCS Humanitas Research Hospital, Milan, Italy; Department of Biomedical Sciences, Humanitas University, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cid+L%22">Cid L</searchLink>; Hospital Alvaro Cunqueiro, Galicia, Spain; Galicia Sur Health Research Institute (IIS Galicia Sur), SERGAS-UVIGO, Vigo, Spain.<br /><searchLink fieldCode="AU" term="%22Cavestro+GM%22">Cavestro GM</searchLink>; Gastroenterology and Gastrointestinal Endoscopy Unit, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Romero-Mascarell+C%22">Romero-Mascarell C</searchLink>; Hospital de la Santa Creu i Sant Pau, Gastroenterology Unit, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gordillo+J%22">Gordillo J</searchLink>; Hospital de la Santa Creu i Sant Pau, Gastroenterology Unit, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Puig+I%22">Puig I</searchLink>; Institut de Recerca i Innovació en Ciències de la Vida i de la Salut a la Catalunya Central (IRIS-CC), Vic, Spain; Digestive Diseases Department, Althaia Xarxa Assistencial Universitària de Manresa, Manresa, Spain; Facultat de Medicina, Universitat de Vic-Central de Cataluña (UVIC-UCC), Vic, Spain.<br /><searchLink fieldCode="AU" term="%22Herraiz+M%22">Herraiz M</searchLink>; University of Navarra Clinic-IdiSNA, Gastroenterology Department, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Betes+M%22">Betes M</searchLink>; University of Navarra Clinic-IdiSNA, Gastroenterology Department, Pamplona, Spain.<br /><searchLink fieldCode="AU" term="%22Herrero+J%22">Herrero J</searchLink>; Complexo Hospitalario Universitario de Ourense, Instituto de Investigación Biomédica Galicia Sur, CIBERehd, Ourense, Spain.<br /><searchLink fieldCode="AU" term="%22Jover+R%22">Jover R</searchLink>; Hospital Universitario de Alicante, Pais Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Balaguer+F%22">Balaguer F</searchLink>; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain; University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pellisé+M%22">Pellisé M</searchLink>; Hospital Clinic Barcelona, Gastroenterology Department, Barcelona, Spain; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Institut d'Investigacions Biomédiques August Pi i Sunyer, Barcelona, Spain; University of Barcelona, Barcelona, Spain. Electronic address: mpellise@clinic.cat.
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  Data: <searchLink fieldCode="JN" term="%22101690683%22">The lancet. Gastroenterology & hepatology</searchLink> [Lancet Gastroenterol Hepatol] 2024 Sep; Vol. 9 (9), pp. 802-810. <i>Date of Electronic Publication: </i>2024 Jul 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+B%2EV%22">Elsevier B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101690683 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2468-1253 (Electronic) <i>NLM ISO Abbreviation: </i>Lancet Gastroenterol Hepatol <i>Subsets: </i>MEDLINE
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