Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish.
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| Title: | Synthesis and Structure of Novel Phenothiazine Derivatives, and Compound Prioritization via In Silico Target Search and Screening for Cytotoxic and Cholinesterase Modulatory Activities in Liver Cancer Cells and In Vivo in Zebrafish. |
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| Authors: | Kisla MM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey.; Graduate School of Health Sciences, Ankara University, 06100 Ankara, Turkey., Yaman M; Interdisciplinary Program in Neuroscience, Bilkent University, 06800 Ankara, Turkey., Zengin-Karadayi F; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey., Korkmaz B; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey., Bayazeid O; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey., Kumar A; Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany., Peravali R; Institute of Toxicology and Genetics (ITG), Karlsruhe Institute of Technology (KIT), 76344 Eggenstein-Leopoldshafen, Germany., Gunes D; Interdisciplinary Program in Neuroscience, Bilkent University, 06800 Ankara, Turkey., Tiryaki RS; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey., Gelinci E; Izmir Biomedicine and Genome Center (IBG), 35340 Izmir, Turkey., Cakan-Akdogan G; Izmir Biomedicine and Genome Center (IBG), 35340 Izmir, Turkey.; Medical Biology Department, Dokuz Eylul University, 35340 Izmir, Turkey., Ates-Alagoz Z; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Ankara University, 06100 Ankara, Turkey., Konu O; Interdisciplinary Program in Neuroscience, Bilkent University, 06800 Ankara, Turkey.; Department of Molecular Biology and Genetics, Bilkent University, 06800 Ankara, Turkey.; UNAM-Institute of Materials Science and Nanotechnology, Bilkent University, 06800 Ankara, Turkey. |
| Source: | ACS omega [ACS Omega] 2024 Jul 03; Vol. 9 (28), pp. 30594-30614. Date of Electronic Publication: 2024 Jul 03 (Print Publication: 2024). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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