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N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules.

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Title: N-Glycosylation-Induced Pathologic Protein Conformations as a Tool to Guide the Selection of Biologically Active Small Molecules.
Authors: Magni A; Department of Chemistry, University of Pavia, 27100, Pavia, Italy., Sciva C; Department of Chemistry, University of Pavia, 27100, Pavia, Italy.; Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131, Milano, Italy., Castelli M; Department of Chemistry, University of Pavia, 27100, Pavia, Italy., Digwal CS; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Rodina A; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Sharma S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Ochiana S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Patel HJ; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Shah S; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Chiosis G; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA., Moroni E; Institute of Chemical Sciences and Technologies (SCITEC), Italian National Research Council (CNR), 20131, Milano, Italy., Colombo G; Department of Chemistry, University of Pavia, 27100, Pavia, Italy.
Source: Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2024 Sep 25; Vol. 30 (54), pp. e202401957. Date of Electronic Publication: 2024 Sep 09.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9513783 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-3765 (Electronic) Linking ISSN: 09476539 NLM ISO Abbreviation: Chemistry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1521-3765
DOI:10.1002/chem.202401957